CAS: 33421-40-8; 5-Phenylpyridin-2-Amine

相似化合物

503536-73-0 87109-10-2 96721-87-8

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CAS号1072-97-5 2-氨基-5-溴吡啶 | CAS号98-80-6 苯硼酸 | CAS号20511-12-0 2-氨基-5-碘吡啶 | CAS号1072-98-6 2-氨基-5-氯吡啶 | CAS号66600-05-3 2-氯-5-苯基吡啶 | CAS号827614-64-2 6-氨基吡啶-3-硼酸频哪醇酯 | CAS号108-86-1 溴苯 | CAS号24388-23-6 苯硼酸频呐醇酯 | CAS号1008-88-4 3-苯基吡啶 | CAS号112-80-1 油酸 | CAS号107351-81-5 2-AMINO-3-METHY... | CAS号107351-82-6 2-溴-5-苯基吡啶 | CAS号107351-80-4 2-氨基-3-溴-5-苯基吡啶 | CAS号105650-23-5 2-氨基-1-甲基-6-苯基咪... | CAS号120281-56-3 2-碘-5-苯基吡啶

3-苯基吡啶置于sodium Amide体系中,用 5,5-Dimethyl-1,3-Cyclohexadiene,甲苯 用作溶剂,化学反应 36.0H,以52%的收率获得2-氨基-5-苯基吡啶
参考文献:2-氨基-1-甲基-6-苯基咪唑并[4,5-B ]吡啶的结构异构体的合成和诱变潜能
标题:2-氨基-1-甲基-6-苯基咪唑并[4,5-B ]吡啶的结构异构体的合成和诱变潜能
摘要:已经进行了2-氨基-1-甲基-6-苯基咪唑并[4,5-B ]吡啶(phip),三个结构异构体和两个去苯基phip同类物的合成.使用鼠伤寒沙门氏菌菌株ta98在ames试验中评估致突变力.与这些杂环胺中的结构特征相关的致突变力增加,从而允许苯基和咪唑并[4,5-B ]吡啶n 2-氨基取代基之间的共振延长.相比之下,Phip异构体的取代不允许苯基参与其氨基咪唑共鸣杂合体,而去苯基同类物的诱变性比phip低86-234倍.
Doi:10.1002/jhet.5570450614

专利信息

专利号:US-8338451-B2
优先权日:2008-03-21
标 题 :Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof
发明人：DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO
权利人:DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO; SANOFI SA
摘要:Compounds of formula (I): n nwherein R, R 1 , R 2 , R 3 , R 4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

专利号:US-8148370-B2
优先权日:2008-03-21
标题 :Polysubstituted derivatives of 2-aryl-6-phenyl-imidazo[1,2-a]pyridines, and preparation and therapeutic use thereof
发明人：DE PERETTI DANIELLE; EVANNO YANNICK
权利人:DE PERETTI DANIELLE; EVANNO YANNICK; SANOFI AVENTIS
摘要:Compounds of formula (I): n nwherein R 1 , R 2 , R 3 , R 4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

专利号:CN-102125875-B
优先权日:2011-01-20
标 题 :Application of ferroceneimine cyclopalladium-phosphine adducts in the synthesis of unsymmetrical biaryl compounds

专利号:CN-102125875-A
优先权日:2011-01-20
标 题 :Application of ferroceneimine cyclopalladium-phosphine adducts in the synthesis of unsymmetrical biaryl compounds

专利号:JP-H1171372-A
优先权日:1997-08-26
标题 :Synthesis of 1-methyl-6-phenylimidazo(4,5-b)pyridine

专利号:JP-2000154189-A
优先权日:1998-11-18
标题 :2-alkoxycarbonylamino-1-methyl-6-phenylimidazo[4,5- b]pyridine derivative and synthesis of 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine using the same derivative