CAS: 636-65-7; (S)-4,5-Diamino-5-Oxopentanoic Acid

相似化合物

19522-40-8 292150-20-0 288149-55-3

上下游产品

CAS号6398-06-7 ZL-谷氨酸α-酰胺 | CAS号1155-62-0 N-苄氧羰基-L-谷氨酸 | CAS号3981-39-3 3-(2,5-dioxo-1,... | CAS号56-86-0 L-谷氨酸 | CAS号86022-82-4 L-isoglutamine ... | CAS号102747-85-3 N2-trityl-L-iso... | CAS号5707-87-9 N-[(Benzyloxy)c... | CAS号55878-80-3 (S)-5-甲氧基-5-氧代-... | CAS号2614-08-6 N-Phthalyl isog... | CAS号6094-36-6 N-苯甲酰-L-谷氨酸 | CAS号25460-87-1 乙酰基-L-谷氨酸α-酰胺

N-Benzyloxycarbonyl-L-Glutamic Acid-1-Hydrazide置于甲醇,乙醇,镍,钯体系中,化学反应生成 L-异谷氨酰胺
参考文献:Narita,Nippon Kagaku Zasshi,1953,Vol. 74,P. 832
标题:Narita,Nippon Kagaku Zasshi,1953,Vol. 74,P. 832

专利信息

专利号:US-2009325821-A1
优先权日:2006-10-10
标题 :In Situ Nucleic Acid Array Synthesis Compositions
发明人：LEPROUST ERIC; PECK BILL J; HUANG XIAOHUA C
权利人:LEPROUST ERIC; PECK BILL J; HUANG XIAOHUA C
摘要:In situ nucleic acid synthesis compositions are provided. The compositions include a solvent; and at least one of: a viscosity modifier; and a surface tension modifier. During use, the compositions further include one of a phosphoramidite and an activator. Also provide are methods of using the compositions, e.g., in the synthesis of nucleic acid arrays, and systems kits for practicing the methods.

专利号:US-6391614-B1
优先权日:1995-07-10
标题:Auxiliary gene and protein of methicillin resistant bacteria and antagonists thereof
发明人：TOMASZ ALEXANDER; DE LENCASTRE HERMINIA
权利人:UNIV ROCKEFELLER
摘要:The present invention is directed to the identification of mutant strains of methicillin resistant bacteria, in particular methicillin resistant Staphylococcus aureus , to identify the characteristics of such bacteria and develop drugs that can reverse, inhibit, or reduce bacterial resistance to beta lactam antibiotics, e.g., methicillin. The invention particularly relates to identification of a novel mutant strain of methicillin resistant S. aureus that manifests a unique phenotype, having a block in cell wall synthesis at or close to the branch point in hexose metabolism involved in the synthesis of cell wall components. Accordingly, the invention provides for methods of treatment and corresponding pharmaceutical compositions for treating bacterial, particularly staphylococcal, infections.

专利号:US-2008221303-A1
优先权日:2004-02-18
标 题:Method for the Preparation of Peptide-Oligonucleotide Conjugates
发明人：KATZHENDLER JEHOSHUA; KLAUZNER YAKIR; BEYLIS IRENA; MIZHIRITSKII MICHAEL; SHPERNAT YAACOV; ASHKENAZI BORIS; FRIDLAND DMITRI
权利人:KATZHENDLER JEHOSHUA; KLAUZNER YAKIR; BEYLIS IRENA; MIZHIRITSKII MICHAEL; SHPERNAT YAACOV; ASHKENAZI BORIS; FRIDLAND DMITRI
摘要:The present invention relates to the synthesis of peptide-oligonucleotide conjugates (POC). More specifically, the invention relates to a novel method for the preparation of peptide-oligonucleotide conjugates, which can be conducted under mild conditions on solid support, can be performed manually or by a synthesizer, can be used to synthesize alternating sequences of peptides and oligonucleotides, and is applicable to the synthesis of a wide variety of peptide-oligonucleotide conjugates constructed from alternate peptide and oligonucleotide blocks.

专利号:US-7105295-B2
优先权日:1999-11-10
标题 :Methods for applying small volumes of reagents
发明人：BASS JAY K; TSO JACQUELINE
权利人:AGILENT TECHNOLOGIES INC
摘要:Methods, devices and apparatus are disclosed for carrying out multiple chemical reactions, such as in situ synthesis of polynucleotides, on a surface comprising an array of discrete sites. Molecules are deposited at a predetermined number of the discrete sites on the surface for reaction at the discrete sites. The surface is positioned relative to an outlet of a fluid ejection device, which is activated to dispense a small volume of a fluid through the outlet to the surface to provide uniform coating of a continuous region of the surface comprising a multiple of the discrete sites. The fluid is dispensed as uniform particles having a diameter such that the uniform particles form a sheet to coat the continuous region of the surface. In one embodiment of the present invention, liquid is dispensed as uniform particles through a fluid ejection device activated by means of ultrasonic energy. The invention has particular application to the in situ synthesis of polynucleotides in arrays on a surface.

专利号:US-12162853-B2
优先权日:2018-10-22
标题:Synthesis of esuberaprost prodrugs
发明人：BATRA HITESH; GUO LIANG
权利人:UNITED THERAPEUTICS CORP
摘要:Provided are novel prodrugs of esuberaprost and pharmaceutical compositions thereof, as well as methods of making and methods of using these prodrugs.

专利号:EP-4424821-A1
优先权日:2023-03-01
标题:Enzymatic synthesis of odilorhabdin and related peptides/proteins comprising non-standard amino acid residues
权利人:MAX PLANCK GESELLSCHAFT
摘要:The present invention relates to a novel method of preparing a non-standard amino acid or a peptide/protein comprising a non-standard amino acid residue, as appropriate, wherein said amino acid residue is selected from 2,4-diamino-3-hydroxybutyrate, L-5-hydroxylysine, L-3-hydroxyarginine, 2,3-didehydroarginine by using enzymatic transformations. Accordingly, the present invention further relates to a method of preparing a peptide/protein comprising one or more non-standard amino acids selected from 2,4-diamino-3-hydroxybutyrate, L-5-hydroxylysine, L-3-hydroxyarginine and 2,3-didehydroarginine. The methods of the present invention are particularly useful in enzyme-assisted preparation of odilorhabdins and their derivatives. The present invention further relates to a polypeptide having 2,4-diaminobutyrate-3-hydroxylase activity and its use for catalyzing a hydroxylation at position 3 of 2,4-diaminobutyrate, to a polypeptide having having L-arginine 3-hydroxylase activity and its use for catalyzing a hydroxylation at position 5 of L-lysine, to a polypeptide having L-arginine 3-hydroxylase activity and its use for for catalyzing a hydroxylation at position 3 of L-arginine, and to a polypeptide having a deacylase activity, which is preferably capable of removing fatty acyl from the N-terminus of an odilorhabdin, and its use for catalyzing a deacylation, preferably for removing a fatty acyl from the N-terminus of an odilorhabdin.