CAS: 72155-45-4; Tert-Butyl (S)-(1-Oxo-3-Phenylpropan-2-yl)Carbamate

上下游产品

CAS号51987-73-6 N-B°C-L-苯丙氨酸甲酯 | CAS号66605-57-0 N-B°C-L-苯丙氨醇 | CAS号87694-53-9 (S)-(1-(甲氧基(甲基)... | CAS号335628-15-4 (4S,5R)-4-benzy... | CAS号1025839-59-1 (S)-4,6-dimetho... | CAS号292150-93-7 B°C-phenylalani... | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号13734-34-4 B°C-L-苯丙氨酸 | CAS号3182-95-4 L-苯丙氨醇 | CAS号142955-51-9 b°C-phe-n-carbo... | CAS号142580-65-2 tert-butyl N-[(... | CAS号149451-80-9 TERT-BUTYL [(1S... | CAS号99281-90-0 (S)-1-氰基-2-苯基乙基... | CAS号72155-48-7 B°C-(3S,4S)-4-氨... | CAS号66605-57-0 N-B°C-L-苯丙氨醇 | CAS号129491-65-2 tert-butyl N-[(... | CAS号98760-08-8 (2R,3S)-1,2-环氧-... | CAS号103127-53-3 (1-氧代-3-苯基丙烷-2-... | CAS号62023-65-8 (2S,3R)-3-(B°C-... | CAS号136522-17-3 (3S,4a,8aS)-2-[...

L-苯丙氨酸乙酯盐酸盐置于二异丁基氢化铝,Sodium Carbonate体系中,用 1,4-二氧六环,水,甲苯 作为反应溶剂,化学反应 3.5H,反应生成 N-Boc-L-苯丙氨醛
参考文献:轻松获取 Evans 的恶唑烷酮.一种新型2-恶唑烷酮衍生物的立体选择性合成及抗菌活性
标题:轻松获取 Evans 的恶唑烷酮.一种新型2-恶唑烷酮衍生物的立体选择性合成及抗菌活性
摘要:开发了一种有趣的新方法来合成埃文斯的手性助剂,收率很高.反过来,另一种新的立体选择性和有效策略也允许从 Morita-Baylis-Hillman 加合物以 34% 的总产率制备 2-恶唑烷酮衍生物.这种恶唑烷酮对从患有乳腺炎感染的动物身上分离的金黄色葡萄球菌菌株进行了测试.
DOI:10.3390/molecules19067429

专利信息

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:EP-0946478-B1
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehydes, ketones and hydroxamic acid compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to processes for the solid-phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-4978744-A
优先权日:1989-01-27
标题:Synthesis of dolastatin 10
发明人：PETTIT GEORGE R; SINGH SHEO B
权利人:UNIV ARIZONA
摘要:A complicated but extremely important scheme of synthesis has been developed for synthesizing, dolaisoleuine, dolaproine, dolaphenine and dolavaline from readily available starting materials such as Z-(S,S)isoleucine, S-phenylalaline, S-phenylalaninol, S-prolinol, S-mandelate, and S-valine. The requisite amino acids have been combined using several peptide coupling procedures to create pharmaceutically pure dolastatin 10.

专利号:US-4599198-A
优先权日:1985-08-02
标题 :Intermediates in polypeptide synthesis
发明人：HOOVER DENNIS J
权利人:PFIZER
摘要:Bis(t-butoxycarbonyl) derivatives of phenylalanylhistidine as intermediates in the synthesis of rennin inhibiting polypeptides.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.