专利号:US-5382665-A 优先权日:1993-03-17 标 题:Synthesis of oxazolines and oxazines 发明人:BENICEWICZ BRIAN C; MITCHELL MICHAEL A 权利人:US ARMY 摘要:A process of preparing an oxazoline or oxazine compound of the formula ##STR1## wherein X is an atom selected from the group of oxygen and sulfur, R is selected from the group consisting of C 1-10 alkyl, C 1-10 fluoroalkyl, aryl and substituted-aryl, and n is 2 or 3 comprising ring-closing a compound of the formula ##STR2## wherein X is an atom selected from the group of oxygen and sulfur, R is selected from the group consisting of C 1-10 alkyl, C 1-10 fluoroalkyl, aryl, and substituted aryl, n is 2 or 3, and Y is a bromine or chlorine atom in the presence of a basic reagent consisting essentially of a fluoride salt supported on an inorganic solid substrate is disclosed together with the compounds, 5-bromomethyl-2-phenyl-1,3-oxazoline, 5-methylene-2-phenyl-1,3-oxazine and 4,4-dimethyl-2-vinyl-1,3-oxazoline.
参考文献:10.1007/978-3-663-19740-9_4 摘要:Asinger F, Saus A. Thiomorpholinsynthesen und Reaktionsverhalten unsubstituierter Thiomorpholin-1.1-dioxide. 1978. In: Oxathiine, Dithiine und Thiomorpholine auf Basis billiger Rohstoffe (Synthesen und Reaktionsverhalten). : VS Verlag für Sozialwissenschaften; 1978.