CAS: 98-09-9; Benzenesulfonyl Chloride

上下游产品

CAS号108-98-5 硫酚 | CAS号98-11-3 苯磺酸 | CAS号882-33-7 二苯二硫醚 | CAS号831-91-4 苄基苯基硫醚 | CAS号515-42-4 苯磺酸钠 | CAS号13865-50-4 甲氧基甲基苯硫醚 | CAS号13509-39-2 Methylthi°Carba... | CAS号934-87-2 S-苯基硫代乙酸酯 | CAS号884-09-3 Benzoic acid, t... | CAS号640-60-8 对甲苯亚磺酸苯酯 | CAS号107267-01-6 2-methyl-3-(phe... | CAS号1050-82-4 Benzenesulfonam... | CAS号106276-56-6 (2-acetylphenyl... | CAS号1111637-97-8 5-Bromo-3-methy... | CAS号111711-89-8 1-(benzenesulfo... | CAS号111711-86-5 1-(benzenesulfo... | CAS号106154-54-5 1-(benzenesulfo... | CAS号10504-97-9 N-[(4-chlorophe... | CAS号111711-85-4 1-(benzenesulfo... | CAS号1096-43-1 Benzenesulfonam...

二氯苯胂置于氯磺酸体系中,化学反应生成 苯磺酰氯
参考文献:Steinkopf; Schubart; Schmidt,Chemische Berichte,1928,Vol. 61,P. 680
标题:Steinkopf; Schubart; Schmidt,Chemische Berichte,1928,Vol. 61,P. 680

专利信息

专利号:US-5760237-A
优先权日:1995-08-25
标 题 :Synthesis of l-azatyrosine using pseudoephedrine as a chiral auxiliary
发明人：MYERS ANDREW G
权利人:CALIFORNIA INST OF TECHN
摘要:A practical synthesis of the potential chemotherapeutic agent L-azatyrosine is described. The key step involved the alkylation of (R,R)-(-)-pseudoephedrine glycinamide with 5-benzenesulfonyloxy-2-iodomethylpyridine and proceeded in 70-95% yield and 89-95% de. Simultaneous hydrolysis of the auxiliary and the benzenesulfonate protecting group afforded L-azatyrosine of ≧99% ee in 73% yield on multigram scale (recovery yield of (R,R)-(-)-pseudoephedrine: 90%).

专利号:US-9988364-B1
优先权日:2017-03-21
标题 :Process for synthesis of Eliglustat and intermediate compounds thereof
发明人：LIU YU; YU GUANNENG; ZHENG ZHIGUO
权利人:ZHEJIANG AUSUN PHARMACEUTICAL CO LTD
摘要:The present invention relates to a process for synthesis of Eliglustat and intermediate compounds thereof. In particular, the present invention relates to a process for synthesis of Eliglustat and pharmaceutically acceptable salts thereof, and relates to the intermediate compounds in the process and a process for preparation of the intermediate compounds.

专利号:US-5861532-A
优先权日:1997-03-04
标 题:Solid-phase synthesis of N-alkyl amides
发明人：BROWN EDWARD G; NUSS JOHN M
权利人:CHIRON CORP
摘要:Methods for solid phase synthesis of N-alkyl amides comprise reductive amination of carbonyl compounds using a reducing agent and an amine-containing linker bound to a solid support. The methods afford high yields of linker-bound, monoalkylated amines, and subsequent coupling with acid derivatives provide derivatized N-substituted amides in excellent yields after cleavage from the solid-phase. Compositions useful in solid phase synthesis are also described.

专利号:US-4910310-A
优先权日:1988-10-03
标 题:Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives
发明人：CAMPBELL ARTHUR L; BEHLING JAMES R; BABIAK KEVIN A; NG JOHN S; MUELLER RICHARD A; FLEET GEORGE W J
权利人:SEARLE & CO
摘要:Novel intermediates and method for the chemical synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives are provided. A preferred intermediate is 1,5-dideoxy-1,5-imino-3, 4-O-isopropylidene-L-fucitol which is used to prepare the HIV inhibitor 1,5-dideoxy-1,5-imino-[N-ω-methyl caproate]-L-fucitol. These compounds are prepared in a short synthesis from the known compound 2,3-O-isopropylidene-D-lyxono-1,4-lactone or in a multi-step synthesis from D-galactose.

专利号:US-8461357-B2
优先权日:2008-09-19
标题 :Expeditious synthesis of gibberellin A5 and esters thereof
发明人：FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS RICHARD P
权利人:FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS R P; UTI LIMITED PARTNERSHIP
摘要:An expeditious synthesis of gibberellin A 5 (GA 5 ) esters is presented, from which GA 5 may be prepared. The synthesis offers an inexpensive route of few steps to these compounds, starting from gibberellin A 3 (GA 3 ) esters in the presence of a metal hydride.

专利号:US-5512701-A
优先权日:1995-06-07
标题:Process for the synthesis of vinyl sulfenic acid derivatives
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.