CAS: 22515-18-0; 4,4-Difluorocyclohexanone

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CAS号176251-49-3 8,8-二氟-1,4-二氧杂螺... | CAS号6317-49-3 4-氧代庚二酸二乙酯 | CAS号539-47-9 2-呋喃丙烯酸 | CAS号4746-97-8 1,4-环己二酮单乙二醇缩酮 | CAS号22515-16-8 4,4-二氟庚二酸二乙酯 | CAS号22515-17-9 5,5-二氟-2-氧代-环己烷羧酸乙酯 | CAS号810659-05-3 4,4-二氟环己基甲胺 | CAS号22419-35-8 4,4-二氟环己醇 | CAS号1150617-90-5 4,4-difluoro-1-...

4-氧代庚二酸二乙酯置于sulfur Tetrafluoride体系中,用 二氯甲烷,水 用作溶剂,化学反应生成4,4-二氟环已酮
参考文献:核磁共振波谱.4,4-二氟环己酮和6,6-二氟-顺-Decal-2-Ones的构象平衡和平衡
标题:核磁共振波谱.4,4-二氟环己酮和6,6-二氟-顺-Decal-2-Ones的构象平衡和平衡
摘要:6,6-Difluoro-Cis-Decal-2-One 和 10-Methyl-6,6-Difluoro-Cis-Decal-2-One 的环倒置率和构象平衡率已使用氟磁共振光谱测定.发现活化能分别为 11.3 +/-0.3 和 9.5 +/-0.1 Kcal/mol.然而,4,4-二氟环己酮似乎在核磁共振时间尺度上甚至在-180O 的构象非等价位点之间快速交换其氟.
Doi:10.1021/ja01027A020

专利信息

专利号:US-9469614-B2
优先权日:2011-10-27
标 题:Synthesis of triazolopyrimidine compounds
发明人：ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

专利号:US-9221829-B2
优先权日:2011-09-14
标题:Synthesis of triazolopyrimidine compounds
发明人：MARAS NENED; ZUPANCIC BORUT
权利人:MARAS NENED; ZUPANCIC BORUT; LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).

专利号:EP-2570405-A1
优先权日:2011-09-14
标题:Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the filed of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of ticagrelor (TGC)

专利号:EP-2586773-A1
优先权日:2011-10-27
标题 :Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

专利号:US-6159673-A
优先权日:1996-07-17
标 题:Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M is a cation. Other oxonol compounds, a light-sensitive material containing an oxonol compound and a process for the synthesis of an oxonol compound are also disclosed.

专利号:US-10053420-B2
优先权日:2015-01-30
标 题 :Processes for the preparation of compounds, such as 3-arylbutanals, useful in the synthesis of medetomidine
发明人：EKLUND LARS; EEK MARGUS; EKAMBARAM RAMESH; MAASALU ANTS
权利人:CAMBREX KARLSKOGA AB
摘要:There is provided a process for the preparation of a compound of formula (I) as defined herein, wherein said process comprises reacting a compound of formula (II) as defined s herein with one or more suitable Vilsmeier reagent.