CAS: 26658-19-5; (2R,3R,4S)-2-((R)-2-Hydroxy-1-(Stearoyloxy)Ethyl)Tetrahydrofuran-3,4-Diyl Distearate

该化合物是一种非离子表面活性剂和乳化剂,通常用于食品,药品和化妆品配方,来自sharpool和八十二酸(静态酸),其特点是由于碳氢化合物链长,具有疏水性,从而增强了其稳定乳液的能力.这种化合物一般是黄色的,褐色的粘膜液体或半固体,取决于温度和配方.

结构式图片

相似化合物

26266-58-0 1338-41-6 1338-39-2

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-9982005-B2
    优先权日:2013-04-04
    标 题 :Macrolides and methods of their preparation and use
    发明人:MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG
    权利人:HARVARD COLLEGE
    摘要:Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.

    专利号:US-2014342177-A1
    优先权日:2011-12-07
    标 题 :Synthesis of cupronickel nanowires and their application in transparent conducting films
    发明人:WILEY BENJAMIN
    权利人:UNIV DUKE
    摘要:A method of synthesis to produce a conductive film including cupronickel nanowires. Cupronickel nanowires can be synthesized from solution, homogeneously dispersed and printed to make conductive films (preferably < 1,000 Ω/sq) that preferably transmit greater than 60% of visible light.

    专利号:US-9149659-B2
    优先权日:2012-11-14
    标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles
    发明人:PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER
    权利人:COTY GERMANY GMBH
    摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.

    专利号:US-11466046-B2
    优先权日:2014-10-08
    标题 :14-membered ketolides and methods of their preparation and use
    发明人:MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG
    权利人:HARVARD COLLEGE
    摘要:Provided herein are methods of preparing new 14-membered ketolides via coupling of an eastern and western half moiety, followed by macrocyclization, and optional functionalization. Intermediates in the synthesis of these ketolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using these ketolides are also provided.

    专利号:US-8106031-B2
    优先权日:2006-05-02
    标题:Hydrolytically-resistant boron-containing therapeutics and methods of use
    发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
    权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC
    摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

    专利号:US-6599972-B2
    优先权日:1996-12-24
    标 题 :Latex compositions containing ethylenically unsaturated esters of fatty compounds and applications thereof
    发明人:THAMES SHELBY FRELAND; PANJNANI KAMLESH GOPICHAND; FRUCHEY OLAN STANLEY
    权利人:UNIV SOUTHERN MISSISSIPPI
    摘要:Novel latex or emulsion compositions containing internally plasticizing and crosslinkable monomers derived from traditional semi-drying or non-drying oils are disclosed and claimed. The monomers are ethylenically unsaturated derivatives of long-chain olefinic compounds. Preferred embodiments include latex formed from acrylate or methacrylate esters of fatty alcohols. A process for the synthesis of the latex composition is also disclosed, which involves (a) polymerization of the ethylenically unsaturated derivatives of a long-chain olefinic compound in an aqueous phase with at least one other copolymerizable monomer; and (b) blending of so formed polymer with at least one drier and a surfactant to form the novel latex or emulsion compositions. These compositions form films at low minimum film forming temperatures (MFT) ranging from -5 to 10° C. and cure to above ambient glass transition (Tg) polymers without the use of traditional organic cosolvents which contribute to environmental pollution via volatile organic compounds (VOCs) emissions. These compositions are therefore useful in waterborne coatings, contact and pressure sensitive adhesives, and inks.
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    主要参考文献

    [参考文献]: Elder Dp, Et Al. Pharmaceutical Excipients - Quality, Regulatory And Biopharmaceutical Considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.
    [参考文献]: Karande P, Et Al. Synergistic Effects Of Chemical Enhancers On Skin Permeability: A Case Study Of Sodium Lauroylsarcosinate And Sorbitan Monolaurate[参考文献]: European Journal Of Pharmaceutical Sciences, 2007, 31(1): 1-7.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 38(S2):60-80,2019
    摘要:Journal of the American College of Toxicology 4(3):65-121, 1985
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