CAS: 465515-31-5; 2-Carboxythiophene-5-Boronic Acid

上下游产品

5-氰基噻吩-2-硼酸 5-Cyanothiophen-2-Ylboronic Acid 305832-67-1

5-氰基噻吩-2-硼酸置于potassium Hydroxide,盐酸体系中,用 甲醇,水 作为反应溶剂,化学反应 6.0H,以78%的收率获得产物5-羧基噻吩-2-硼酸
参考文献:Method For The Production Of Boronic Acids Carrying Cyanoalkyl,Carboxyl And Aminocarbonyl Groups And Their Derivatives
标题:Method For The Production Of Boronic Acids Carrying Cyanoalkyl,Carboxyl And Aminocarbonyl Groups And Their Derivatives
摘要:一种通过将化合物的公式(iii)与brønsted碱y(oh)在溶剂或溶剂混合物中转化为氨基羰基硼酸(iv)的制备方法,其中z代表可选择取代的芳基,杂芳基,烯烃,杂烯烃,烷基亚烯,杂烷基亚烯,烯基亚烯,杂烯基亚烯,炔基亚烯,芳基烷基亚烯,杂芳基烷基亚烯,芳基杂烷基亚烯,杂芳基杂烷基亚烯,烷基杂芳基,杂烷基杂芳基或烷基芳基基团;y代表价数为0<5的金属或铵阳离子;b代表硼酸,硼酸酯或硼酸盐,或硼酸酐.公式(iv)的氨基羰基硼酸可以进一步水解形成公式(v)的羧基硼酸.< Div="">

专利信息

专利号:US-8221719-B2
优先权日:2007-09-05
标 题:Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof
发明人：PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI
权利人:PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.

专利号:US-11299484-B2
优先权日:2018-10-10
标 题 :Inhibiting fatty acid synthase (FASN)
发明人：MARTIN MATTHEW W; ZABLOCKI MARY-MARGARET; MENTE SCOT; DINSMORE CHRISTOPHER; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.