专利号:US-10011567-B1 优先权日:2017-03-09 标题 :Method for the synthesis of acrylate derivatives 发明人:WANG MINGWEN; ZHANG YUE 权利人:INNOSCI LLC 摘要:The present invention provides an improved synthesis of a salt of acrylate derivatives. The synthesis generally includes the preparation of an ester or an amide containing a leaving group followed by the formation of a salt.
专利号:WO-2025122636-A1 优先权日:2023-12-04 标题:Method for the synthesis of acrylate derivatives 发明人:CAICEDO-CARVAJAL CARLOS; KATZ JORDAN; CHOI SEAN 权利人:ORTHOBOND CORP 摘要:The disclosure relates to the synthesis of quaternary salts of various acrylates in high yield and high purity.
专利号:WO-2011106986-A1 优先权日:2010-03-02 标题:Inhibitors of hepatitis c virus ns5b polymerase 发明人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO 权利人:MERCK SHARP & DOHME; MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO 摘要:Compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and /or viral production in a cell-based system. Wherein Z, R 30 , R 40 , R 50 and R 60 of compounds of formula (I) are herein defined as in the description.
专利号:US-8551237-B2 优先权日:2007-12-10 标 题 :Synthesis of colorants in mixing apparatus 发明人:LOEBEL JOHANNES 权利人:LOEBEL JOHANNES; BASF SE 摘要:A process for preparing colorants of the general formula (Ia), (Ib) or (Ic) n nor mixtures thereof, comprises reactingn (a) tetracarboxylic acids or their functional derivatives with (b) at least one compound selected fromn i. aliphatic amines, ii. aromatic amines, iii. aliphatic diamines, iv. aromatic diamines, n (c) optionally in the presence of further additives, (d) optionally in the presence of wetting agentsn nin a mixing apparatus. These colorants are useful for coloration of macromolecular organic and inorganic materials of natural and synthetic origin.
专利号:US-6432294-B1 优先权日:2000-12-14 标题 :Electrochemical activation of organic disulfides for electrophilic substitution 发明人:GLASS RICHARD S; JOUIKOV VIATCHESLAV V; BOJKOVA NINA V 权利人:UNIV ARIZONA 摘要:Electrochemical oxidation of organic disulfides is conducted in an electrolytic solution containing an arene (e.g., anthracene, acenaphthylene, phenanthrene), and depending on the arene used and/or the product desired, an organic base (e.g., pyridine) to effect the synthesis of organothiated products in good yields.
专利号:US-11117893-B2 优先权日:2018-09-24 标题 :Methods for preparation of substituted pyridines and related novel compounds 发明人:WATKINS EDMOND BLAKE; UREDI DILIPKUMAR; MOTATI DAMODER REDDY 权利人:WATKINS EDMOND BLAKE; UREDI DILIPKUMAR; MOTATI DAMODER REDDY; UNION UNIV 摘要:The present invention relates to novel methods of preparation of substituted pyridines and the compounds produced therefrom. In particular, the present invention provides efficient methods for the construction of diversely substituted pyridines, with varying substitution patterns under simple and metal-free conditions with high atom- and pot-economy and excellent functional group tolerance, and which are useful for the synthesis of natural products.
摘要:Shaabani, A.; Sarvary, A.; Shaabani, S., Science of Synthesis: Multicomponent Reactions, (2013) 2, 103. 摘要:K. Clarke and K. Rothwell. J. Chem. Soc. 1960, 1885. 摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129. 摘要:A. Fischer, W.J. Galloway and J. Vaughan. J. Chem. Soc., B 1964, 3591. 摘要:H.H. Perkampus and G. Prescher. Ber. Bunsenges. Physik. Chem. 72, 429 (1968).