CAS: 7149-10-2; 4-(Aminomethyl)-2-Methoxyphenol Hydrochloride

上下游产品

CAS号2874-33-1 香草肟 | CAS号93249-67-3 2-methoxy-4-[(m... | CAS号121-33-5 香草醛 | CAS号121-33-5 香草醛 | CAS号2444-46-4 辣椒素 | CAS号31078-36-1 癸酸香草酰胺 | CAS号128007-31-8 N-[(4-羟基-3-甲氧基苯... | CAS号19408-84-5 二氢辣椒素 | CAS号1196-92-5 4-(氨基甲基)-2-甲氧基苯酚 | CAS号69693-13-6 帕凡尼 | CAS号852923-26-3 N-[(4-hydroxy-3... | CAS号89575-10-0 N-[(4-hydroxy-3... | CAS号89575-11-1 N-[(4-hydroxy-3...

香草醛置于盐酸,Palladium 10% On Activated Carbon,盐酸羟胺,氢气,Sodium Acetate Trihydrate体系中,用 乙醇,水 作为反应溶剂,20.0~80.0 °C,101.33 Kpa 条件下,反应 26.0H,反应生成 香兰素胺盐酸盐
参考文献:疏水链的延长作为一个分子开关:辣椒素衍生物和内源性脂质作为潜在的瞬态受体潜在的香草通道2拮抗剂的发现.
标题:疏水链的延长作为一个分子开关:辣椒素衍生物和内源性脂质作为潜在的瞬态受体潜在的香草通道2拮抗剂的发现.
摘要:瞬时受体电位香草2型(trpv2)蛋白是非选择性ca 2+由于缺乏可用的选择性和有效的药理学工具和内源性调节剂,Trpv亚家族的可渗透通道成员仍被认为是孤立的trp通道.在这里,我们描述了通过完全基于配体的方法发现的新型合成长链辣椒素衍生物作为强效trpv2拮抗剂(与完全无活性的辣椒素相比),它们的疏水链的作用以及这些衍生物的结构-活性关系如何导致的发现.,以鉴定充当trpv2拮抗剂的内源性长链脂肪酸乙醇酰胺或伯酰胺.合成的和内源性的拮抗剂都表现出对以不同的动力学特征为特征的已知trpv2激动剂的不同抑制作用.
DOI:10.1021/acs.Jmedchem.8B00734

专利信息

专利号:US-11891351-B2
优先权日:2020-03-20
标 题 :Synthesis of capsaicin derivatives
发明人：LAGER ERIK
权利人:AXICHEM AS
摘要:The present invention relates to the synthesis of capsaicin derivatives, specifically to the synthesis of 6-heptyne derivatives of capsaicin.

专利号:US-2024229089-A1
优先权日:2021-04-30
标 题 :A process for enzymatic synthesis of amides from amines and carboxylic acids or esters
发明人：LIN SHUANGZHENG; CORDOVA ARMANDO; DEIANA LUCA; IBRAHEM ISMAIL
权利人:XP CHEMISTRIES AB
摘要:The present invention relates to A process for enzymatic synthesis of amides of formula (III) from amines of formula (I) and compounds of formula (II). characterized in that the lipase is immobilized on a rotary bed reactor or on a spin-fixed-bed reactor and a Dean-Stark apparatus is used for dehydration.

专利号:US-8710268-B2
优先权日:2007-07-31
标题:Method for the hydrolysis of substituted formylamines into substituted amines
发明人：BOBYLEV MIKHAIL
权利人:BOBYLEV MIKHAIL
摘要:An improved method for the synthesis of substituted formylamines and substituted amines via an accelerated Leuckart reaction. The Leuckart reaction is accelerated by reacting formamide or N-alkylformamide and formic acid with an aldehyde or a ketone at a preferred molar ratio that accelerates the reaction. The improved method is applicable to various substituted aldehydes and ketones, including substituted benzaldehydes. An accelerated method for the hydrolysis of substituted formylamines into substituted amines using acid or base and a solvent at an elevated temperature. The improved method is useful for the accelerated synthesis of agrochemicals and pharmaceuticals such as vanillylamine, amphetamine and its analogs, and formamide fungicides.

专利号:US-2017266353-A1
优先权日:2014-05-13
标 题:Bioadhesive compounds and methods of synthesis and use
发明人：MURPHY JOHN L; RADANO CHRISTOPHER P; DALSIN JEFFREY L; KOEPSEL JUSTIN T
权利人:DSM IP ASSETS BV
摘要:Synthesis methods for creating polymeric compounds comprising phenyl derivatives (PD), or PDp i.e., polymers modified with PD, with desired surface active effects are described. The polymer backbone of PDp has structural or performance features that can be tailored to control physical properties of PDp, allowing it to be useful for different applications i.e., tissue adhesives or sealants, adhesion promoting coatings, and antifouling coatings.

专利号:US-2023060251-A1
优先权日:2020-03-20
标 题 :Synthesis of capsaicin derivatives

专利号:WO-2009018353-A1
优先权日:2007-07-31
标题 :Improved method for the synthesis of substituted formylamines and substituted amines