CAS: 13668-61-6; 2-(Cyclopent-2-En-1-yl)Acetic Acid

该化合物是一种多功能的箱式酸衍生物,其特点是环戊基替代物,为合成应用提供了独特的反应性.其结构将不饱和的循环性运动与乙酸组的功能多功能性结合起来,使其在有机合成中具有价值,特别是对于循环化和功能化反应而言.该化合物是制药,农用化学品和精美化学品的制作中的关键中间体.其环球叶素成分能够参与二星-阿尔德和其他循环添加反应,而碳箱酸组则允许进一步衍生.该产品通常以高纯度供应,确保要求高的合成工艺的一贯性.

结构式图片

相似化合物

15848-49-4 2410641-71-1 2275348-11-1

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

环戊-2-烯-1-乙酸甲酯 Cyclopent-2-Enyl-Essigsaeure-Methylester 20006-85-3
(δ2-Cyclopenten-1)-Malonsaeure 197455-87-1

合成工艺路线路线简述

    (Rs)-2-Cyclopentenecarbonyl Chloride置于吡啶,Lithium Aluminium Tetrahydride,氯化亚砜体系中,用 乙醚 用作溶剂,化学反应生成2-环戊烯基-1-乙酸
    参考文献:Branner-Jorgensen,S.; Berg,A.,Acta Chemica Scandinavica (1947),1966,Vol. 20,P. 2192-2194
    标题:Branner-Jorgensen,S.; Berg,A.,Acta Chemica Scandinavica (1947),1966,Vol. 20,P. 2192-2194

    海关参考信息

    专利信息


    专利号:WO-9832790-A1
    优先权日:1997-01-27
    标 题:Porous articles with surface functionality and uses thereof
    发明人:KOONTZ STEVEN L; DEVIVAR RODRIGO V; FABRICANT JILL D; GOLDKNOPF IRA L
    权利人:FLOWGENIX CORP; KOONTZ STEVEN L; DEVIVAR RODRIGO V; FABRICANT JILL D; GOLDKNOPF IRA L
    摘要:Porous organic articles having no surface functionality may be treated by remote plasma discharge to introduce oxygen or nitrogen atoms directly bonded to the surface of the article, including the interstitial surface. These oxygen and nitrogen atoms provide chemical handles through which a variety of useful moieties can be bonded to the article. Modified porous organic articles are useful in the solid phase synthesis of biomolecules when nucleosides, amino acids, or their derivatives are bonded directly or indirectly to the nitrogen or oxygen atoms. Alternatively, porous solid supports can be treated to introduce chromatographically active groups, such as an anion exchanger, a cation exchanger, an hydrophobic group, a hydrazide group, a reactive group of covalent bond formation through protein amino groups, a substituent group for reversed phase chromatography, and a substituent group for chiral chromatography. Moreover, surface-functionalized porous articles comprising an immobilized diagnostic agent can be used for diagnosing or monitoring patient conditions and diseases.

    专利号:EP-3049072-A1
    优先权日:2013-09-25
    标 题:Synthesis of delta 12-pgj3 and related compounds

    专利号:WO-2015048268-A1
    优先权日:2013-09-25
    标题 :Synthesis of delta 12-pgj3 and related compounds

    专利号:TW-568914-B
    优先权日:1996-12-23
    标题 :Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

    专利号:CN-1242007-A
    优先权日:1996-12-23
    标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds

    专利号:PT-951466-E
    优先权日:1996-12-23
    标题:CYTOALQUIL COMPOUNDS, LACTAMA, LACTONE AND RELATED, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THE SAME, AND METHODS FOR INHIBITING Î’-AMYLOID PEPTIDE RELEASE AND / OR ITS SYNTHESIS BY THE USE OF SUCH COMPOUNDS
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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Dagousset, G.; Masson, G., Science of Synthesis Knowledge Updates, (2015) 1, 413.
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