CAS: 18362-30-6; 2-Chloro-6-Hydroxybenzaldehyde

上下游产品

3-chloro-o-cresol 2-chloro-6-fluorobenzaldehyde 3-mon°Chlorophenol chloroform 5-Chlor-2H-1-benzopyran-2-on ethyl 4-chlorobenzofuran-2-carboxylate 6-acetoxy-2-chlorobenzaldehyde Acetic acid (2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-(3-chloro-2-formyl-phenoxy)-tetrahydro-pyran-3-yl ester

2-氯-6-氟-苯甲醛置于potassium Hydroxide体系中,用 水,二甲基亚砜 用作溶剂,以91%的收率获得6-氯水杨醛
参考文献:Icetexane 天然产品的策略
标题:Icetexane 天然产品的策略
摘要:Icetexane 二萜是丰富复杂的多环天然产物,已被描述为具有多种生物活性.我们在此报告了一种基于两步烯醇化物烷基化和闭环复分解反应序列的针对这些有趣合成目标的 6-7-6 三环核心结构的一般合成方法.
Doi:10.1002/ejoc.201800707

专利信息

专利号:US-10759743-B2
优先权日:2016-10-24
标 题 :Pd-catalyzed γ-C(sp3)-H arylation / heteroarylation of free amines
发明人：YU JIN-QUAN
权利人:SCRIPPS RESEARCH INST
摘要:Pd(II)-catalyzed g-G(sp3)-H arylation or heteroarylation of primary amines is realized by using 2-hydroxynicotinaldehyde as a catalytic transient directing group. Importantly, the catalyst and the directing group loading can be lowered to 2% and 4% respectively, thus demonstrating high efficiency of this newly designed transient directing group. Heterocyclic aryl iodides are also compatible with this reaction. Furthermore, swift synthesis of 1,2,3,4-tetrahydronaphthyridine derivatives is accomplished using this reaction.

专利号:US-2987525-A
优先权日:1958-10-29
标题:Synthesis of polycyclic heterocyclic compounds
发明人：ARRIGO JOSEPH T
权利人:UNIVERSAL OIL PROD CO

专利号:US-4151201-A
优先权日:1976-08-13
标 题:Process for preparing 2-hydroxybenzoic aldehydes
发明人：CASIRAGHI GIOVANNI; CASNATI GIUSEPPE; PUGLIA GIUSEPPE; SARTORI GIOVANNI; TERENGHI GIULIANA
权利人:MONTEDISON SPA
摘要:There is disclosed a catalytic process for preparing, from phenols and formaldehyde 2-hydroxybenzoic aldehydes some of which are new in the art and, more particularly, a high-selectivity process for preparing the aldehydes by direct synthesis from phenols having at least a free ortho position and formaldehyde, in the presence of a catalyst consisting of anhydrous stannous and/or stannic chloride and of an aprotic binder.