5-Phenylazo-Pyrimidin-2-Ylamine置于1,4-二氧六环,镍体系中,化学反应生成2,5-二氨基嘧啶 参考文献:Hensel,Festschr. C. Wurster S. 135,139 标题:Hensel,Festschr. C. Wurster S. 135,139
专利信息
专利号:US-2022356182-A1 优先权日:2009-03-27 标题 :Inhibitors of hepatitis c virus replication 发明人:COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOLL RICHARD; ZHONG BIN; ZHU JIAN 权利人:MERCK SHARP & DOHME 摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
专利号:US-11053243-B2 优先权日:2009-03-27 标 题:Inhibitors of hepatitis C virus replication 发明人:COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN 权利人:MERCK SHARP & DOHME 摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
专利号:US-9090661-B2 优先权日:2009-03-27 标 题:Inhibitors of hepatitis C virus replication 发明人:COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN 权利人:MERCK SHARP & DOHME 摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
专利号:JP-2000281611-A 优先权日:1999-03-30 标 题 :Synthesis of phenolic compound having protected hydroxy group, and radioactive ray-sensitive composition by using the same
专利号:CN-117050024-B 优先权日:2023-10-13 标题:A kind of synthesis method of 2-amino-4,6-dichloro-5-carboxamidopyrimidine
专利号:CN-117050024-A 优先权日:2023-10-13 标 题:A kind of synthesis method of 2-amino-4,6-dichloro-5-carboxamidopyrimidine
参考标题: Inhibitors Of Hepatitis C Virus Replication Inhibiteurs De La Réplication Du Virus De L'Hépatite C 摘要:The Present Invention Relates To Compounds Of Formula (I) That Are Useful As Hepatitis C Virus (Hcv) Ns5A Inhibitors, The Synthesis Of Such Compounds, And The Use Of Such Compounds For Inhibiting Hcv Ns5A Activity, For Treating Or Preventing Hcv Infections And For Inhibiting Hcv Viral Replication And/or Viral Production In A Cell-Based System.
合成参考文献
摘要:D. J. Brown and J. Harper. J. Chem. Soc. 1963, 1276.