专利号:US-12240808-B2 优先权日:2021-05-28 标 题 :Process for the synthesis of calebin-a and its intermediates 发明人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; MUTHUKAMAN NAGARAJAN; NAIDU PENTAKOTA PARADESI 权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; MUTHUKAMAN NAGARAJAN; NAIDU PENTAKOTA PARADESI 摘要:The invention discloses novel intermediates in the synthesis of Calebin A represented by formula 3. The invention also covers processes for the synthesis of Calebin-A and its analogs using compounds of formula 3.
专利号:US-6350878-B1 优先权日:1998-05-18 标 题 :Intermediates for the synthesis of epothilones and methods for their preparation 发明人:ALTMANN KARL-HEINZ; BAUER ARMIN; SCHINZER DIETER 权利人:NOVARTIS AG 摘要:The invention relates to a method of synthesis for a compound of formula (I),wherein R is a heterocyclyl moiety and X1, X2, X3 and X4 are, independently of each other, protecting groups, which is appropriate for the synthesis of epothilone B and desoxyepothione B.
专利号:US-5359016-A 优先权日:1993-03-29 标 题 :Process for the synthesis of styrene-isoprene rubber 发明人:HSU WEN-LIANG; HALASA ADEL F; MATRANA BARRY A 权利人:GOODYEAR TIRE & RUBBER 摘要:The subject invention relates to a technique for synthesizing rubbery copolymers of styrene and isoprene. These rubbery copolymers exhibit an excellent combination of properties for utilization in tire tread rubber compounds. By utilizing these styrene-isoprene rubbers in tire treads, tires having improved wet skid resistance can be built without sacrificing rolling resistance or tread wear characteristics. This invention more specifically discloses a process for the synthesis of styrene-isoprene rubbers which comprises copolymerizing isoprene monomer and styrene monomer in an organic solvent in the presence of a catalyst system which is comprised of (a) a lithium initiator and (b) an alkyl tetrahydrofurfuryl ether modifier, wherein the molar ratio of the modifier to the lithitium initiator is within the range of 2:1 to 40:1. The subject invention further discloses a process for the synthesis of styrene-isoprene rubbers which comprises copolymerizing isoprene monomer and styrene monomer in an organic solvent in the presence of a catalyst system which is comprised of (a) a lithium initiator and (b) 2,2-ditetrahydrofurylpropane as a modifier, wherein the molar ratio of the modifier to the lithium initiator is within the range of 1:1 to 40:1.
专利号:US-2023286893-A1 优先权日:2022-03-09 标题 :Vanillylidenechloroacetone and its use thereof in synthesis of calebin-a 发明人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; MUTHUKAMAN NAGARAJAN; PENTAKOTA PARADESI NAIDU 权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; MUTHUKAMAN NAGARAJAN; PENTAKOTA PARADESI NAIDU 摘要:The present invention discloses a compound, Vanillylidenechloroacetone (VCA)—1-Chloro-4-(4′-hydroxy-3′-methoxy-phenyl)-but-3-en-2-one, and the process of preparing the same. The invention also discloses a process for synthesis of Calebin-A from Vanillylidenechloroacetone.
专利号:US-4670563-A 优先权日:1984-06-20 标题 :Imidazolides as intermediates for the synthesis of cytotoxic conjugates 发明人:JANSEN FRANZ; GROS PIERRE 权利人:SANOFI SA 摘要:Imidazolides of the formula: ##STR1## in which: E represents an inert spacing structure; and n G represents a group: ##STR2## or a group --S--S--X, in which X is an activating group. Application: synthesis of cytotoxic conjugates.
专利号:WO-2022127640-A1 优先权日:2020-12-16 标题:Process for synthesis of furan-based diamines 发明人:GUO RUIJING; PIRES RAUL; BEUCK SASKIA; LATORRE MARTINEZ IRENE CRISTINA; PAN XIANGCHENG; JIANG YUAN 权利人:COVESTRO DEUTSCHLAND AG; GUO RUIJING 摘要:The invention provides a process for the synthesis of furan-based diamines based on renewable resources.
摘要:Shimada, K., Science of Synthesis Knowledge Updates, (2010) 1, 425. 摘要:Shimada, K., Science of Synthesis Knowledge Updates, (2010) 1, 441. 摘要:Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -(44), 1982 摘要:Van, H. (ed.). OPD Chyemical Buyer's Directory 1989. 76th ed, New York, NY: Schnell Publishing Co., Inc. 1989., p. 240 摘要:IMDG; International Maritime Dangerous Goods Code; International Maritime Organization p.6069, 6070 (1988)