相似化合物
539-17-3 60-11-7 3010-57-9物理性质
- 熔点111°C
- 沸点371.0±25.0 °C at 760 mmHg
- 闪点178.2±23.2 °C
- 密度1.0±0.1 g/cm3
- PH:2.9(red)-4(yellow/orange)
- pKa:3.226(at 25°C)
- PSA:27.96
- LogP:4.168
- 折射率1.567
- 蒸汽压0.0±0.8 mmHg at 25°C
- 溶解性Insoluble In Water; Soluble In Ethanol, Benzene, Ether, Chloroform,Petroleum Ether, Mineralacids, Oils
- 敏感性4-DIMETHYLAMINOAZOBENZENE can detonate, particularly if sensitized by the presence of metal salts or strong acids. May form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides.
- 外观形态黄色粉末
- 储存条件常温保存.
- 产品应用用作醇溶黄和PH指示剂.
- 性质描述金黄色片状物或粉末.熔点114-117°C.溶于醇,醚,氯仿,苯,石油醚和无机酸,不溶于水.
欧盟法规
ECHA物质ECHA物质ECHA物质C&L通报REACH预注册上下游产品
CAS号121-69-7 N,N-二甲基苯胺 | CAS号2684-02-8 benzenediazonium | CAS号82946-80-3 1-(4-N,N'-dimet... | CAS号2747-31-1 N,N-dimethyl-4-... | CAS号101-61-1 4,4'-四甲基二氨基二苯甲烷 | CAS号369-57-3 四氟硼酸重氮苯盐 | CAS号13921-67-0 N,N-dimethyl-4-... | CAS号138-89-6 N,N-二甲基-4-亚硝基苯胺 | CAS号100-63-0 苯肼 | CAS号2491-74-9 4'-硝基-4-二甲氨基偶氮苯 | CAS号3837-55-6 3'-硝基-4-二甲氨基偶氮苯 | CAS号99-98-9 对氨基-N,N-二甲基苯胺 | CAS号2747-31-1 N,N-dimethyl-4-... | CAS号3010-38-6 N,N-Dimethyl-4-... | CAS号60-09-3 4-阿基苯甲酯 | CAS号621-90-9 4-(甲氨基)偶氮苯 | CAS号2491-52-3 對硝偶氮苯合成工艺路线路线简述
- 合成目标产物 Solvent Yellow 2 主要起始原料 N,N-Dimethylaniline And Aniline
- (文献来源)合成步骤主要原料 N,N-Dimethylaniline 和 Aniline
4,4'-双(二甲氨基)偶氮苯置于potassium Tert-Butylate,氢气,溶剂黄146体系中,用 四氢呋喃,乙醇 作为反应溶剂,40.0~130.0 °C,3.0 Mpa 条件下,反应 60.0H,反应生成 溶剂黄 2
参考文献:偶氮 (N=n) 键与胺的锰催化氢化
标题:偶氮 (N=n) 键与胺的锰催化氢化
摘要:我们报告了第一个使用地球丰富金属络合物对偶氮化合物的 N=n 键进行均相催化氢化的例子.氢化反应由锰钳络合物催化,在温和条件下进行,并产生胺,这使得该方法成为偶氮化合物转化的可持续替代途径.基于机理研究提出了一种涉及金属-配体合作和肼中间体的合理机制.
DOI:10.1002/adsc.202100440
专利信息
专利号:WO-2023039068-A1
优先权日:2021-09-08
标题:Compositions and methods for synthesis of peptide nucleic acid intermediates
发明人:COULL JAMES M; GILDEA BRIAN D
权利人:NEUBASE THERAPEUTICS INC
摘要:The present disclosure provides intermediates for the synthesis of peptide nucleic acid (PNA) backbones and monomers, such as cyclic intermediates, and methods of making the same.
专利号:US-2004030209-A1
优先权日:2000-11-30
标 题:Method for the production of alkyl aryl sulphonates
发明人:NARBESHUBER THOMAS; STEINBRENNER ULRICH; KRACK GERHARD
摘要:The preparation of alkylaryl compounds takes place by n 1) preparation of a mixture of, on statistical average, predominantly monobranched C 10-14 -olefins by n a) reaction of a C 4 -olefin mixture over a metathesis catalyst for the preparation of an olefin mixture comprising 2-pentene and/or 3-hexene, and optional removal of 2-pentene and/or 3-hexene, followed by dimerization of the resulting 2-pentene and/or 3-hexene over a dimerization catalyst to give a mixture comprising C 10-12 -olefins, and optionally removal of the C 10-12 -olefins, or n b) extraction of predominantly monobranched paraffins from kerosene cuts and subsequent dehydrogenation, or n c) Fischer-Tropsch synthesis of olefins or paraffins, where the paraffins are dehydrogenated, or n d) dimerization of shorter-chain internal olefins, or n e) isomerization of linear olefins or paraffins, where the isomerized paraffins are dehydrogenated, n 2) reaction of the olefin mixture obtained in stage 1) with an aromatic hydrocarbon in the presence of an alkylation catalyst which contains zeolites of the faujasite type.
专利号:US-12358952-B2
优先权日:2021-01-19
标 题 :Compositions and methods of synthesizing shape shifting cyclic peptides (Sscp) and their use in the identification of novel therapeutic compounds
发明人:STOWELL MICHAEL; OLD WILLIAM; WORRELL BRADY; MAYER JOHN
权利人:UNIV COLORADO REGENTS
摘要:The invention described herein includes a novel platform for the development of novel shapeshifting drug-like compounds that overcome physical mass limitations as they possess the ability to interconvert internally and spontaneously, i.e., shapeshift, between multiple chemical structures with varying pharmacophore properties. In one preferred embodiment, the invention include systems, methods, and compositions for the synthesis of novel bullvalene amino acid (Bvas) compounds that may further be incorporated into Shape Shifting Cyclic Peptides (SSCP) with varying pharmacophore properties and their use as novel therapeutic compounds.
专利号:WO-8504598-A1
优先权日:1984-04-05
标题:Catalyst, process for its preparation and use thereof in conversion of synthesis gas to hydrocarbons
发明人:ATKINS MARTIN PHILIP; NAY BARRY
权利人:BRITISH PETROLEUM CO PLC
摘要:A composition suitable for use after activation as a catalyst or a support therefor in the conversion of synthesis gas to hydrocarbons comprising a porous, essentially amorphous framework matrix comprising at least one element present in the form of a hydrolysed compound thereof, for example silicon and aluminium, and distributed uniformly throughout the framework matrix at least one metal selected from Groups VIa and VIII of the Periodic Table, for example iron, cobalt, nickel and/or ruthenium. Also a process for the production of the composition involving a hydrolysis step and a process for converting synthesis gas to hydrocarbons using the activated composition as catalyst.
专利号:US-11970523-B2
优先权日:2018-07-25
标 题 :Long-acting oxyntomodulin hybrid peptide, preparation method therefor, and application thereof
发明人:QIAN HAI; HUANG WENLONG; CAI XINGGUANG; LI CHENGYE; LIU CHUNXIA; DAI YUXUAN
权利人:UNIV CHINA PHARMA
摘要:The present invention discloses a polypeptide and application thereof. By modifying oxyntomodulin (OXM), hybridizing OXM with a peptide sequence of Exenatide, including enabling the polypeptide to be resistant to DPP-4 enzyme degradation through amino acid modification, and conjugating fatty acid chains at the same time, an OXM hybrid peptide having longer pharmacologic action time and better weight losing effects is obtained. Synthesis of a target polypeptide is fast realized by an orthogonal protection strategy solid-phase synthesis method, and a crude product is purified and freeze-dried to obtain the OXM hybrid peptide.
专利号:EP-4622991-A2
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide