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专利信息
专利号:US-2024228455-A1
优先权日:2021-04-27
标 题 :Synthesis of cbn and cbnv
发明人:KAVARANA MALCOLM J
权利人:TEEWINOT LIFE SCIENCES CORP
摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.
专利号:US-3846399-A
优先权日:1969-04-10
标题:Process for controlled stepwise synthesis of polypeptides
发明人:HIRSCHMANN R; DENKEWALTER R
权利人:MERCK & CO INC
摘要:The invention disclosed herein relates to a novel process for the controlled, stepwise synthesis of polypeptides and proteins. More particularly, it is concerned with a process for the rapid and efficient preparation of polypeptides in which multiple sequential steps are carried out without isolation of intermediate peptides. This process for the controlled stepwise synthesis of polypeptides involves reacting a starting amino acid or peptide (or derivative thereof) with an N-carboxy amino acid anhydride (or derivative thereof) in an aqueous medium under conditions of controlled pH such that the only amino group present in appreciable concentration in reactive form during the course of the reaction is the amino group in the starting amino acid or peptide.
专利号:US-6420599-B2
优先权日:1998-05-29
标 题:Chemical process for the stereoselective synthesis of R-(-)-carnitine
发明人:MARZI MAURO; TINTI MARIA ORNELLA; DE ANGELIS FRANCESCO
权利人:SIGMA TAU IND FARMACEUTI
摘要:A process is described for the stereoselective synthesis of R-(-)-carnitine in which the characterizing step is condensation of glycerol with an amine of (-)camphorsulfonic acid.
专利号:US-4578485-A
优先权日:1984-02-08
标 题 :Synthesis of spectinomycin analogs by an improved Grignard process
发明人:WHITE DAVID R
权利人:UPJOHN CO
摘要:The invention concerns a method for the synthesis of 6'-ethyl spectinomycin and analogs thereof, including intermediates utilized in the method. The method comprises converting an enamine by a Grignard addition to various novel dienones not hitherto known. The dienones are then hydrogenated and deblocked to obtain 6'-ethyl spectinomycin and analogs thereof. The 6'-ethyl spectinomycin and analogs thereof prepared by the invention exhibit especially good antibacterial activity.
专利号:US-2014171631-A1
优先权日:2011-08-09
标题:Synthesis of catechin and epicatechin conjugates
发明人:ACTIS GORETTA LUCAS; VITON FLORIAN; BARON DENIS MARCEL; DIONISI FABIOLA
权利人:ACTIS GORETTA LUCAS; VITON FLORIAN; BARON DENIS MARCEL; DIONISI FABIOLA; NESTEC SA
摘要:The present invention relates generally to catechin and epicatechin conjugates of formula (I). For example, a chemical synthesis process for the preparation of catechin and epi-catechin compounds, in particular of catechin and epi-catechin conjugates is disclosed. A further aspect of the invention pertains to new catechin and epi-catechin conjugate compounds.
专利号:US-7667034-B2
优先权日:2004-06-23
标题:Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer
发明人:SENTHILKUMAR UDAYAMPALAYAM PALANISAMY; PADMANABHAN RAMAR; SIVASANKARAN VENUGOPAL; MOHAN SINGARAVEL
权利人:ORCHID CHEMICALS & PHARM LTD
摘要:This invention relates to an improved process for the industrial manufacture of S-adenosyl-L-methionine (SAMe) of formula (I), which consists of stereo-selective methylation of S-adenosyl-L-homocysteine (SAH) with the enrichment of active (S,S)-isomer.