专利号:WO-0063152-A1 优先权日:1999-02-22 标题:Acetylated and related analogues of chicoric acid as hiv integrase inhibitors 发明人:BURKE TERRENCE R; ZHAIWEI LIN; ZHAO HE; NEAMATI NOURI; POMMIER YVES 权利人:US HEALTH; BURKE TERRENCE R; ZHAIWEI LIN; ZHAO HE; NEAMATI NOURI; POMMIER YVES 摘要:Chicoric acid analogues and derivatives have activity against HIV-1 integrase. The structural features that are required for this activity are elucidated by assaying these analogues and derivatives against HIV-1 integrase. Furthermore, methods of synthesis of the enantiomers of chicoric acid itself, as well as its analogues and derivatives, are disclosed. Additionally, methods of use of chicoric acid analogues and derivatives to inhibit HIV-1 integrase are disclosed, as are compositions comprising chicoric acid analogues and derivatives.
专利号:CN-102796746-A 优先权日:2012-08-07 标题:A gene segment regulating the synthesis of Solanaceae flavonoids and caffeoylquinic acid and its application
专利号:CN-102796746-B 优先权日:2012-08-07 标题 :Gene segment for regulating synthesis of solanaceae flavonoids and caffeoyl quinic acid, and uses thereof
专利号:CN-114395566-B 优先权日:2022-03-28 标题:Application of sweet potato ERF transcription factor IbERF4 in promoting synthesis of plant chlorogenic acid substances
专利号:JP-2009207492-A 优先权日:2008-02-06 标 题 :Enzymatic synthesis of cinnamic acid derivatives
专利号:CN-114395566-A 优先权日:2022-03-28 标题:Application of sweet potato ERF transcription factor IbERF4 in promoting the synthesis of chlorogenic acids in plants
参考文献:10.1016/s0026-895x(25)09385-x 摘要:Robinson WE, Cordeiro M, Abdel-Malek S, Jia Q, Chow SA, Reinecke MG, Mitchell WM. Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: inhibition of the core catalytic domain of human immunodeficiency virus integrase. Molecular Pharmacology. 1996 Oct;50(4):846–55. doi: 10.1016/s0026-895x(25)09385-x.