CAS: 3586-12-7; 3-Phenoxyaniline

该化合物是一种有机化合物,其特征是存在一种丙烯和苯氧化合物,其分子结构特征是代之以氨基(-NH2)和苯氧(-O-苯)的苯环,在元体位置上,该化合物一般在室温时是固体,在染料,药物和农用化学合成中具有潜在用途,在有机溶剂中表现出中等溶性,在水中溶性有限,这对许多芳香胺来说很常见,氨基组的存在允许氢结合,影响其再活性和与其他化学物种的互动.此外,3-苯氧苯并可能构成某些健康风险,因为许多醋酸衍生物可能是有毒或致癌的,因此需要在实验室和工业环境中仔细处理和采取适当的安全措施.其化学特性使它成为有机合成中有价值的中间体,特别是在开发较复杂的分子的过程中.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

1-nitro-3-phenoxybenzene 3-chloro-aniline phenol m-Bromoaniline chloro-acetic acid-(3-phenoxy-anilide) 1-(3-phenoxy-phenyl)-biguanide 5-phenoxy-2-pyridin-2-yl-benzothiazole 1-Benzoyl-3-(3-phenoxy-phenyl)-thiourea

合成工艺路线路线简述

  • 合成目标产物 3-Phenoxyaniline 主要起始原料 3-Bromoaniline And Phenol
  • (文献来源)合成步骤主要原料 3-Bromoaniline 和 Phenol
Potassium Phenolate置于乙醇,镍体系中,化学反应生成 3-苯氧基苯胺
参考文献:Sova Et Al.,Collection Of Czechoslovak Chemical Communications,1959,Vol. 24,P. 1170
标题:Sova Et Al.,Collection Of Czechoslovak Chemical Communications,1959,Vol. 24,P. 1170

海关参考信息

专利信息


专利号:US-10808079-B2
优先权日:2015-03-27
标 题:Synthesis of copolyimides containing fluorine and silicon surface modifying agents
发明人:CONNELL JOHN W; WOHL JR CHRISTOPHER J; DOSS JEREME R; CROW ALLISON M; KIM WILLIAM T; LIN YI
权利人:NASA
摘要:Various embodiments provide random copolyimides that may possess the mechanical, thermal, chemical and optical properties associated with polyimides yet achieve a low energy surface. In various embodiments, the copolyimides may be prepared using a minor amounts of a diamino terminated fluorinated alkyl ether oligomer and a diamino terminated siloxane oligomer. The various embodiments include processes for making the copolyimides containing fluorine and silicon surface modifying agents and anisotropic coatings and articles of manufacture from them. Thus the coatings and articles of manufacture made with the copolyimides of the various embodiments may be characterized as having an anisotropic fluorine and silicon composition and low surface energy.

专利号:US-10557210-B2
优先权日:2014-02-24
标题 :Direct electrochemical synthesis of doped conductive polymers on metal alloys
发明人:KINLEN PATRICK JOHN; LAWLESS LAWRENCE MICHAEL
权利人:BOEING CO
摘要:This disclosure relates generally to the discovery of improved methods of reducing corrosion on metals and metal alloys without using hexavalent chromium reagents. More particularly, the disclosure relates to preparing corrosion resistant metals using doped conducting polymers such as polyaniline (PANI) on metal alloys such as aluminum alloys.

专利号:US-5817850-A
优先权日:1997-10-30
标 题 :Ferrocene bis(phosphonite) ligands and complexes for transition-metal-catalyzed reactions
发明人:PASTOR STEPHEN D; SHUM SAI P
权利人:CIBA SC HOLDING AG
摘要:The synthesis of new sterically hindered ferrocene bis(phosphonites) of formula I ##STR1## the synthesis of the corresponding transition-metal complexes and the use of these complexes in transition-metal-catalyzed reactions are described.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-5916899-A
优先权日:1996-10-18
标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人:KIELY JOHN S; GRIFFITH MICHAEL C
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.

专利号:JP-6856608-B2
优先权日:2014-02-24
标 题:Direct electrochemical synthesis of dope conductive polymer on metal alloy
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合成参考文献


参考文献:10.1055/s-0036-1590819
摘要:Stradiotto M, MacQueen P. Nickel-Catalyzed Cross-Coupling of Ammonia or Primary Alkylamines with (Hetero)aryl Sulfamates, Carbamates, or Pivalates. Synlett. 2017 Jul 14;28(13):1652–6. doi: 10.1055/s-0036-1590819.
参考文献:10.1021/jm020528+
摘要:Reinhard EJ, Wang JL, Durley RC, Fobian YM, Grapperhaus ML, Hickory BS, Massa MA, Norton MB, Promo MA, Tollefson MB, Vernier WF, Connolly DT, Witherbee BJ, Melton MA, Regina KJ, Smith ME, Sikorski JA. Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein. J Med Chem. 2003 May 22;46(11):2152–68. doi: 10.1021/jm020528+.
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