(甲氧基甲基)环氧乙烷置于高氯酸,水体系中,用83%的收率获得产物3-甲氧基-1,2-丙二醇 参考文献:Crown Cation Complex Effects. 22. Enhancement Of Cation Binding In Lariat Ethers Bearing A Methyl Group At The Quaternary,Pivot Carbon Atom 标题:Crown Cation Complex Effects. 22. Enhancement Of Cation Binding In Lariat Ethers Bearing A Methyl Group At The Quaternary,Pivot Carbon Atom 摘要: DOI:10.1021/jo00156A018
专利号:US-7288198-B2 优先权日:2004-03-15 标题 :Removal of alcohols and water from a methylcyclopentadiene recycle stream in a process for the synthesis of methylcyclopentadienyl manganese tricarbonyl 发明人:MARCHAND DAVID M; KADKHODAYAN ABBAS 权利人:AFTON CHEMICAL CORP 摘要:During the process of synthesis of methylcyclopentadienyl manganese tricarbonyl (MMT), a key raw material methylcyclopentadiene (MCP) is used. The MCP component may be recycled for subsequent reaction processes. The recycle stream of MCP is washed with water and, optionally, passed over a molecular sieve bed to remove the contaminants protic side products from the MCP recycled stream.
专利号:WO-2021262906-A1 优先权日:2020-06-23 标题:Synthesis of complex insect pheromone blends and reaction apparatuses for the same 发明人:GLENN WESLEE; SHEPPARD MICAH; NGUYEN KIM; WU KATI; LEE TONI; HEEL THOMAS; ROZZELL DAVID; LEONARD EFFENDI 权利人:PROVIVI INC 摘要:This disclosure concerns methods and apparatuses for the synthesis of insect pheromones and precursors thereof in a scalable and eco-friendly fermentation reaction; for example, by converting saturated or unsaturated substrate feedstocks utilizing exogenous and endogenous metabolic machinery.
专利号:US-8877171-B2 优先权日:2010-02-03 标 题 :Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis 发明人:LICHA KAI; SCHIRNER MICHAEL; WELKER PIA; HAAG RAINER; WEINHART MARIE; PAULUS FLORIAN 权利人:LICHA KAI; SCHIRNER MICHAEL; WELKER PIA; HAAG RAINER; WEINHART MARIE; PAULUS FLORIAN; MIVENION GMBH 摘要:The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations.
专利号:US-6242602-B1 优先权日:1999-03-29 标 题:One pot synthesis of 5,10-dihydrophenazine compounds and 5,10-substituted dihydrophenazines 发明人:GIRI PUNAM; BYKER HARLAN J; BAUMANN KELVIN L 权利人:GENTEX CORP 摘要:Dihydrophenazines and bis(dihydrophenazines) are prepared in high yield under commercially viable reaction conditions by reacting a catechol with a 1,2-diaminoaryl compound, wherein either the catechol or the 1,2-diaminoaryl compound is provided in at least 50% molar stoichiometric excess. The product may be oxidized to the corresponding phenazine, but is preferably derivatized at one or both of the 5,10-positions to form a monosubstituted or disubstituted dihydrophenazine or bis(dihydrophenazine). Most preferably, 5,10-dialkyl-5,10-dihydrophenazines are prepared starting from catechol and 1,2-diaminoaryl compound in a one pot synthesis. The products are useful as dyes, and in particular as chromophores in electrochromic systems.
专利号:US-10961539-B2 优先权日:2015-06-11 标题 :Promoter system inducing expression by 3-hydroxypropionic acid and method for biological production of 3-hydroxypropionic acid using same 发明人:PARK SUNG-HOON; ZHOU SHENGFANG; ASHOK SOMASUNDAR; SEOL EUN HEE; AINALA SATISH KUMAR 权利人:NOROO IC CO LTD; NOROO R&C CO LTD 摘要:The present invention relates to a promoter system inducing expression of 3-hydroxypropionic acid (3-HP) and a method of biologically producing 3-HP using the same. To improve production of 3-HP in a biological manner, continuous synthesis of new enzymes having enzyme activity is necessary. As a result of screening 3-HP reactive transcription regulators and 3-HP reactive promoters from several microorganisms including Pseudomonas denitrificans , it was confirmed that the transcriptions regulations and promoters are composed of LysR proteins and particular gene nucleotide sequences binding to the LysR proteins. Therefore, the 3-HP inducible system is expected to be effectively used to regulate 3-HP metabolic pathways.
[参考文献]: P Schuff-Werner, Et Al. 1-O-Methyl-Rac-Glycerol: A New Agent For The Cryopreservation Of Mononuclear Cells. Cryobiology. 1988 Dec;25(6):487-94.
合成参考文献
摘要:Kleoff, M.; Omoregbee, K.; Zimmer, R., Science of Synthesis Knowledge Updates, (2018) 4, 214. 摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 2004. Toxicity, Repellency of Phytotoxicity of 979 Chemicals to Birds, Mammals and Plants. Research Report No. 04-01. National Wildlife Research Center, Fort Collins, Colorado. 118 pp. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/U_schafer041_2004.pdf