CAS: 85089-31-2; 1-Chloro-2-Fluoro-3-Methylbenzene

专利信息

专利号:WO-2023114200-A2
优先权日:2021-12-14
标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof

专利号:US-9771356-B2
优先权日:2012-09-21
标题 :Inhibitors of beta-hydroxylase for treatment of cancer
发明人：WANDS JACK R; DE LA MONTE SUZANNE; AIHARA ARIHIRO; OLSEN MARK JON; THOMAS JOHN-MICHAEL
权利人:RHODE ISLAND HOSPITAL; UNIV MIDWESTERN
摘要:The present invention relates to compounds which modulate (e.g., inhibit) the activity of beta-hydroxylase (e.g., Asparatyl (asparaginyl) β-hydroxylase (ASPH)), including novel 2-aryl-5-amino-3(2H)-furanone and 2-heteroaryl-5-amino-3(2H)-furanone compounds, pharmaceutical compositions thereof, methods for their synthesis, and methods of using these compounds to modulate the activity of ASPH in an a cell-free sample, a cell-based assay, and in a subject. Other aspects of the invention relate to use of the compounds disclosed herein to ameliorate or treat cell proliferation disorders.

专利号:EP-2906540-A1
优先权日:2012-10-12
标 题:An improved production method and new intermediates of synthesis of elvitegravir

专利号:EP-2906540-B1
优先权日:2012-10-12
标题 :An improved production method and new intermediates of synthesis of elvitegravir
发明人：RADL STANISLAV
权利人:ZENTIVA KS

专利号:WO-2023114198-A2
优先权日:2021-12-15
标题 :Methods for the synthesis of complement factor d inhibitors

专利号:WO-2014056465-A1
优先权日:2012-10-12
标题 :An improved production method and new intermediates of synthesis of elvitegravir