CAS: 27489-62-9; Trans-4-Aminocyclohexanol

上下游产品

CAS号1380214-98-1 trans-4-azid°Cy... | CAS号50910-54-8 反式-4-氨基环己醇盐酸盐 | CAS号123-30-8 对氨基苯酚 | CAS号103-90-2 对乙酰氨基苯酚 | CAS号100-02-7 对硝基苯酚 | CAS号27489-60-7 反-4-乙酰氨基环己醇 | CAS号71118-96-2 trans-4-Aethoxy... | CAS号3685-26-5 反式-4-羟基环己烷羧酸 | CAS号623-11-0 对硝基甲苯 | CAS号106006-83-1 2,6-二氨基-4,5,6,7... | CAS号104618-31-7 2-(4-羟基环己基)异吲哚-... | CAS号149506-81-0 4-(dibenzylamin... | CAS号4248-19-5 氨基甲酸叔丁酯 | CAS号22348-44-3 反式-4-甲基氨基-环己醇 | CAS号29493-38-7 TRANS-4-CBZ-AMI... | CAS号27489-63-0 (反式-4-羟基环己基)氨基甲酸苄酯 | CAS号99337-98-1 反式-2-(4-羟基-环己基)... | CAS号224309-64-2 4-(叔丁氧羰基氨基)环己醇

对氨基苯酚 在 Palladium On Activated Charcoal,氢气,Potassium Carbonate体系中,用 丙酮作为反应溶剂,100.0 °C,1.2 Mpa 条件下,反应 7.0H,以90%的收率获得trans-4-Aminoyclohexanol
参考文献:一种制备反式对氨基环己醇的方法
标题:一种制备反式对氨基环己醇的方法
摘要:本发明公开了一种制备反式对氨基环己醇的方法,该方法以对氨基苯酚为原料,加入金属催化剂,以碳酸盐或硫酸盐为添加剂,在酮类溶剂中经加氢反应得到对氨基环己醇,再经后处理得到反式对氨基环己醇.本发明采用了相对廉价的对氨基苯酚,代替较贵的乙酰氨基苯酚,降低了生产成本,提高了经济效益,且经实验探索,发现该制备过程反应相对平缓,反应温度和反应压力大大下降,便于操作,适合工业化生产.反应所得产品收率可达80‑90%,反式对氨基环己醇比例高,对环境污染小.

专利信息

专利号:US-9950988-B2
优先权日:2012-12-26
标题:Method for the synthesis of alpha/alpha-prime-alcoxylated glycerol linear carbonic esters
发明人：LEISING FRéDéRIC; MOULOUNGUI ZéPHIRIN
权利人:CHRYSO; INST NAT POLYTECHNIQUE TOULOUSE; INST NAT DE LA RECH AGRONOMIQUE INRA
摘要:A method for the synthesis of α/α′-alcoxylated glycerol linear carbonic esters, wherein the following are brought into contact at a reaction temperature lower than 220° C.: a quantity of at least one precursor selected from the group consisting of α/α′-alcoxylated glycerol cyclo-carbonates; a quantity of at least one catalyst selected from the group consisting of metal oxides, Lewis acids, organometallic catalysts and mineral bases; and a quantity of at least one organic primer. A composition containing at least one novel α/α′-alkoxylated glycerol linear carbonic ester.

专利号:US-7314843-B2
优先权日:2004-01-29
标 题:Method for synthesis of lamellar solids from an amino-alcohol-type organic structuring agent
发明人：BAREA EVA; FORNES VICENTE; CORMA AVELINO; BOURGES PATRICK; GUILLON EMMANUELLE
权利人:INST FRANCAIS DU PETROLE
摘要:The invention relates to a process for synthesis of lamellar solids based on silicates comprising:n i) a mixing stage, during which a mixture that comprises an alkaline metal, a silica source, water and an organic structuring agent is prepared, and ii) a crystallization stage during which this mixture is kept under conditions allowing the formation of a crystalline solid. nn The organic structuring agent that is used in this process comprises an alcohol group and an amine group that are separated by a hydrocarbon chain.

专利号:WO-2012020271-A1
优先权日:2010-08-11
标题 :Process for the preparation of montelukast sodium
发明人：BODI JOZSEF; FARAGO JANOS; SZOEKE KATALIN; UJVARI VIKTOR; TEMESVARI KRISZTINA; ARANYI ANTAL; SANTA ZSUZSANNA; NAGY MELINDA MAGDOLNA
权利人:RICHTER GEDEON NYRT; BODI JOZSEF; FARAGO JANOS; SZOEKE KATALIN; UJVARI VIKTOR; TEMESVARI KRISZTINA; ARANYI ANTAL; SANTA ZSUZSANNA; NAGY MELINDA MAGDOLNA
摘要:The present invention relates to a process for the synthesis of Montelukast sodium of formula I the chemical name of which is [(R)-(E)]-1-[[[1-[3-[2-(7-chloro-2- quinolinyl)ethenyl]phenyl] -3 - [2-( 1 -hydroxy- 1 -methylethyl)phenyl]propyl] thio]methyl] - -cyclopropaneacetic acid sodium salt. The present invention further provides compounds of general formulae V, VI, VIb and VIII as new intermediates.

专利号:US-5174980-A
优先权日:1991-10-04
标题 :Synthesis of crystalline ZSM-35
发明人：HELLRING STUART D; STRIEBEL RANDY F
权利人:MOBIL OIL CORP
摘要:This invention relates to a new form of crystalline material identified as having the structure of ZSM-35, to a new and useful method for synthesizing said crystalline material and to use of said crystalline material prepared in accordance herewith as a catalyst for organic compound, e.g. hydrocarbon compound, conversion.

专利号:US-7115737-B2
优先权日:2003-05-05
标题:Solid phase synthesis of novel biaryl triazine library by suzuki cross coupling
发明人：CHANG YOUNG-TAE
权利人:UNIV NEW YORK
摘要:Two methods are used to produce diaryl trisubstituted triazines. In the first method, cyanuric chloride is first reacted with a 4-alkoxybenzylamine. The product of this reaction is then reacted with a resin-bound amine, such as 4-alkoxybenzylamine, to ensure that the final compound will be bound to a resin. The product of this reaction is then reacted with boronic acid to produce a trisubstituted diaryl triazine. In the second method, cyanuric chloride is reacted with a benzenealkanethiol. The product of this reaction is then reacted with a resin-bound amine, such as 4-alkoxybenzylamine, to ensure that the final compound will be bound to a resin. The product of this reaction is then reacted with m-CPBA to form a sulfone, which is then reacted with a 4-alkoxybenzylamine to form the desired trisubstituted biaryltriazine.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.