CAS: 54827-17-7; 3,3',5,5'-Tetramethyl-[1,1'-Biphenyl]-4,4'-Diamine

相似化合物

312693-82-6 1184980-29-7 119777-61-6

上下游产品

CAS号24596-18-7 4-氯-2,6-二甲基苯胺 | CAS号24596-19-8 4-溴-2,6-二甲基苯胺 | CAS号603-77-0 2,6-二甲基苯肼 | CAS号144653-01-0 2-bromo-5-(4-br...

2,2',6,6'-Tetramethylazobenzene-N,N'-Dioxide置于盐酸,Sodium Hydrogen Sulfide,硫酸,甲烷,一水合肼,Sodium Thiosulfate,Sodium Hydroxide体系中,用 甲醇,水,氯苯 作为反应溶剂,化学反应 9.0H,反应生成 3,3',5,5'-四甲基联苯胺
参考文献:一种生化制剂tmb的合成方法
标题:一种生化制剂tmb的合成方法
摘要:本发明公开了一种生化制剂tmb的合成方法,包括如下步骤:1,2,2',6,6'‑偶氮四甲苯胺‑n,N‑二氧化物的合成;2,2,2',6,6'‑四甲基二苯肼的合成;3,Tmb.(1/2)H2So4的合成;4,Tmb.2Hcl的制备;5,Tmb的制备.该方法合成路线简单,原料便宜易得,合成成本低,而且收率高.

专利信息

专利号:US-2005019901-A1
优先权日:2002-01-31
标题 :Methods for synthesis of bio-active nanoparticles and nanocapsules for use in optical bio-disc assays and disc assembly including same
发明人：MATVEEVA EVGENIA; VALENCIA RAMONCITO MAGPANTAY; WERNER MARTINA ELISABETH
摘要:Optical bio-disc assays and synthesis of bio-active nanoparticles and nanocapsules for use therewith. Related methods for synthesis of polymeric nanoparticles for use in disc assays include forming reverse micelles having an outer non-polar shell and an inner polar cavity and solubilizing in the reverse micelles a polymerizing mixture including monomers, co-monomers, weakly polar monomers, and/or polymerizable surfactants. This may also include an initiator of polymerization. The methods also include polymerizing the mixture. The invention is also directed to the use of the nanoparticles and nanocapsules in optical bio-disc assays for the detection of analytes including nucleic acid sequences. Related optical assay discs and disc systems are also provided.

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-2025154014-A1
优先权日:2022-02-15
标 题 :Continuous flow synthesis of mesoporous silica particles
发明人：KULKARNI AMOL ARVINDRAO; JUNDALE RAJASHRI BABURAO; BARI ATUL HARISHCHANDRA
权利人:COUNCIL SCIENT IND RES
摘要:The present invention discloses a continuous flow synthesis of mesoporous silica particles by using a reactor at shorter reaction times. The particle size of mesoporous silica particles are in the range of 400 nm-1.5 microns. and is monodispersed. surface area >700 m2/g and pore size in the range of 2-4 nm.

专利号:US-8536153-B2
优先权日:2008-11-04
标 题 :Chemical synthesis of phosphatidylinositol mannoside glycans from Mycobacterium tuberculosis
发明人：SEEBERGER PETER H; BOONYARATTANAKALIN SIWARUTT; LEPENIES BERND
权利人:SEEBERGER PETER H; BOONYARATTANAKALIN SIWARUTT; LEPENIES BERND; MAX PLANCK GESELLSCHAFT
摘要:The efficient synthesis of phosphatidylinositol mono- to hexa-mannoside (PIM 1 to PIM 6 ) is reported. The invention relates to these phosphatidylinositol mono- to hexa-mannosides carrying a linker and a reactive functional group, e.g. the sulfhydryl group, a protein, a fluorescent probe, or a solid phase. The invention further relates to vaccines comprising the PIMs linked to a carrier protein or an antigen.

专利号:US-10047122-B2
优先权日:2013-03-14
标 题 :Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use
发明人：QIAN WENJIAN; PARK JUNG EUN; LAI CHRISTOPHER C; KELLEY JAMES A; LEE KYUNG S; BURKE JR TERRENCE R
权利人:THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:The invention provides novel compounds that may serve as anticancer therapeutics. The compounds of the invention bind to polo-like kinases through the polo-box domain. In certain embodiments, the compounds of the invention are POM-protected peptide derivatives. The use of cationic bis-alkyl his residues in combination with a mono POM-protected phophoryl group results in a peptide possessing an overall neutral charge. The peptide derivatives of the invention have achieved both good efficacy and an enhanced bioavailability. The invention also provides methods of use, compositions, and kits thereof. Further, the invention provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

专利号:US-7384739-B2
优先权日:2001-11-14
标题 :Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
发明人：KITABAYASHI MASAO; KUROITA TOSHIHIRO; ISHIDA YOSHIKAZU; KOMATSUBARA HIDEYUKI; NISHIYA YOSHIAKI; OKA MASANORI; KAWAMURA YOSHIHISA; IMANAKA TADAYUKI
权利人:TOYO BOSEKI
摘要:The invention provides methods, kits, and compositions for enhancing synthesis of DNA involving a carboxylate ion-supplying substance that is effective in promoting DNA synthesis in enzymatic DNA synthesis reactions. The invention further provides a thermostable DNA polymerase-related factor derived from Thermococcus species, which has an activity to promote the DNA synthesis activity of DNA polymerase or which binds to DNA polymerase.