CAS: 461-58-5; N-Cyanoguanidine

上下游产品

azido-N-cyanoformamidinate dicyandiazide CYANAMID nitrosoguanidine6-piperidino-[1,3,5]-triazine-2,4-diamine 1-phenylbiguanide 2,4-diamino-6-(2-furyl)-1,3,5-triazine 2,4-diamino-6-(2′-pyridyl)-1,3,5-triazine

N-氰亚胺基-S,S-二硫代碳酸二甲酯 以 乙醇 作为反应溶剂,化学反应生成 二聚氰胺
参考文献:Crf Receptor Antagonists And Methods Relating Thereto
标题:Crf Receptor Antagonists And Methods Relating Thereto
摘要:本发明揭示了具有治疗多种疾病作用的crf受体拮抗剂,包括用于治疗表现为crf高分泌的温血动物(如中风)的疾病.本发明的crf受体拮抗剂具有以下结构:包括立体异构体,前药和其药用可接受盐,其中m,R,R1,R2,A,X,Y和z的定义如本文所述.还披露了含有crf受体拮抗剂与药用可接受载体组合的组合物,以及其使用方法.

专利信息

专利号:US-2025313590-A1
优先权日:2024-03-16
标题:Phosphoramidite morpholino monomers towards synthesis/convergent synthesis of PMO, TMO, their chimera oligos in 5 prime to 3 prime direction
发明人：SINHA SURAJIT; GHOSH ATANU; BANERJEE ARPAN
权利人:INDIAN ASS FOR THE CULTIVATION OF SCIENCE
摘要:The present invention relates to 5′-morpholino amidite monomers as 5′-CE/5′- t Bu phosphoramidite morpholino monomers (2) and process chemistry for the efficient synthesis of N-Trityl or monomethoxytrityl (MMTr)-protected 5′-morpholino amidite monomers and their use in the synthesis of phosphorodiamidate morpholino oligonucleotides (PMO), thiophosphoramidate morpholino oligonucleotides (TMO) and their chimeras which can be used for antisense technology or in general oligonucleotides related research.

专利号:US-2022401910-A1
优先权日:2019-12-02
标 题 :Apparatus for the synthesis of oligonucleotides and process for the preparation thereof
发明人：AEMISSEGGER ANDREAS; DUGOVIC BRANISLAV; JAUKER MARIO; STAUSS MARTIN
权利人:BACHEM AG
摘要:The present invention provides apparatuses and methods for the synthesis of oligonucleotides and related compounds. In particular, the present invention allows to effectively prepare reagents to be fed into an apparatus for the synthesis of such oligomers.

专利号:US-2024391773-A1
优先权日:2023-05-23
标 题 :Direct synthesis of improved superhydrophobic carbon nitride co-products, and improved superhydroppbic carbon nitride co-products thereof
发明人：LY THUC HUE; THI QUOC HUY; Man Ping
权利人:UNIV CITY HONG KONG
摘要:The present invention is concerned with a method of direct synthesis of co-products of at a first co-product and a second co-product. The first co-product is superhydrophilic carbon nitride thin film and the second co-product is superhydrophilic carbon nitride powder. The method has a step of using a guanidine carbonate salt as a precursor material. The present invention is also concerned with carbon nitride co-products. The carbon nitride co-products has a first co-product of superhydrophilic carbon nitride thin film and a second co-product of superhydrophilic carbon nitride powder. The superhydrophilic carbon nitride thin film has chemical formula of CN x , wherein x is 0.86-1.04, and the superhydrophilic carbon nitride powder has a chemical formula of g-C 3 N 4 .

专利号:US-2024368099-A1
优先权日:2022-01-18
标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes
发明人：SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS
权利人:HENKEL AG & CO KGAA
摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.

专利号:US-2023287032-A1
优先权日:2020-08-14
标 题:Synthesis of fluorinated nucleotides
发明人：CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO
权利人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO; MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2′-(S)-fluoro-thio-adenosine monophosphate or 2′-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

专利号:US-2022274917-A1
优先权日:2019-09-06
标题 :Solvent free continuous process for the synthesis of metformin hyrochloride
发明人：KULKARNI AMOL ARVIND; SHARMA BRIJESH
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a continuous solvent free and additive free process for the synthesis of Metformin Hydrochloride in a screw reactor. >90% conversion of the solid substrates without solvent is obtained in a screw reactor to produce Metformin Hydrochloride with at least 90% selectivity.