CAS: 89028-40-0; (R)-4-Isopropyl-3-Propionyloxazolidin-2-One

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77877-19-1 80697-93-4 150895-71-9

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propionyl chloride (R)-4-isopropyloxazolidin-2-one (4S)-4-isopropyl-1,3-oxazolidin-2-one propionic acid anhydride (2R,3S,4R)-N-methoxy-5-(4-methoxybenzyl)oxy-N,2,4-trimethyl-3-(triethylsilyl)oxy-pentanamide (4R,2'R,3'S,4'S)-3-(5'-Benzyloxy-3'-hydroxy-2',4'-dimethylpentanoyl)-4-isopropyl-2-oxazolidinone -3-(7-benzoyloxy-5-benzyloxy-6-methoxy-3-(4-methoxybenzyl)oxy-2,8-dimethyl-1-oxononyl)-4-isopropyl-2-oxazolidinone3(2R,3S,5R,6S,7R),4R-3-(7-benzoyloxy-5-benzyloxy-6-methoxy-3-(4-methoxybenzyl)oxy-2,8-dimethyl-1-oxononyl)-4-isopropyl-2-oxazolidinone (3(2R,3S,5R,6S,7R),4R)-3-(7-benzoyloxy-5-benzyloxy-3-hydroxy-6-methoxy-2,8-dimethyl-1-oxononyl)-4-isopropyl-2-oxazolidinone

(S)-4-异丙基-2-唑烷酮,丙酸酐置于(R)-Hbtm,N,N-二异丙基乙胺体系中,用 氘代氯仿 作为反应溶剂,化学反应 3.0H,反应生成 (R)-(-)-4-异丙基-3-丙酰基-2-恶唑烷酮
参考文献:Absolute Configuration Of Lactams And Oxazolidinones Using Kinetic Resolution Catalysts
标题:Absolute Configuration Of Lactams And Oxazolidinones Using Kinetic Resolution Catalysts
摘要:A Simple Method For Determining The Absolute Configuration Of Oxazolidinones,Lactams,And Their Derivatives Using Kinetic Resolution Catalysts Is Described. The Optically Pure Substrates Were Acylated Using The (S)-Hbtm And The (R)-Hbtm Catalyst,And The Faster Reaction Was Determined. An Empirical Mnemonic Was Developed For The Assignment Of The Absolute Configuration Based On The Fast-Reacting Catalyst.
DOI:10.1021/ol303239T