CAS: 1526-17-6; 6-Fluoro-2-Nitrophenol

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53981-25-2 364-31-8 82419-26-9

上下游产品

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2-氟苯酚置于三氯异氰尿酸,Bismuth Subnitrate/charcoal体系中,用 二氯甲烷 用作溶剂,化学反应 1.0H,以85%的收率获得2-氟-6-硝基苯酚
参考文献:在非质子条件下在三氯异氰尿酸存在下使用亚硝酸铋/木炭选择性硝化苯酚
标题:在非质子条件下在三氯异氰尿酸存在下使用亚硝酸铋/木炭选择性硝化苯酚
摘要:摘要描述了一种在室温下在ch2Cl2中存在三氯异氰尿酸的情况下使用亚硝酸铋/木炭温和,高效且区域选择性的方法,用于酚类化合物的单硝化.
Doi:10.1016/j.Cclet.2010.05.016

专利信息

专利号:US-2016194279-A1
优先权日:2012-12-09
标 题 :One pot process for the conversion of aroyl chlorides to acyl thioureas
发明人：CHEPURI VENKATA RAMANA; BEERAN SENTHILKUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R′ is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R″ and R′″ are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.

专利号:US-9096624-B2
优先权日:2009-06-01
标 题:Amino pyrimidine anticancer compounds
发明人：CREW ANDREW P; SHERMAN DAN; APPARI RAMA DEVI; CHEN XIN; CHILUKURI RAMESH; DONG HANQING; FERRARO CATERINA; FOREMAN KENNETH; GUPTA RAMESH C; LI AN-HU; STOLZ KATHRYN M; VOLK BRIAN; ZAHLER ROBERT
权利人:OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula 1, as shown below and defined herein: n n n n n n n n n n n n and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers mediated at least in part by FAK.