CAS: 1813-33-8; 2-Chloro-4-(Trifluoromethyl)Benzonitrile

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CAS号82096-91-1 2-氯-4-(三氟甲基)苯甲醛 | CAS号581813-20-9 (2-氯-4-(三氟甲基)苯基)甲胺

2-氯-4-(三氟甲基)苯甲醛置于2,2,6,6-四甲基哌啶氧化物,2,4,5,6-四(9H-咔唑-9-基)异酞腈,Ammonium Acetate体系中,用 乙腈 用作溶剂,以55 %的收率获得2-氯-4-三氟甲基苯腈
参考文献:可见光催化无金属醛和铵合成腈
标题:可见光催化无金属醛和铵合成腈
摘要:开发了一种在极其温和的条件下在空气中由醛和铵盐合成腈的绿色方法,即1,2,3,5-四(咔唑-9-基)-4,6-二氰基苯(4Czipn)作为以光催化剂,2,2,6,6-四甲基哌啶-1-氧基(tempo)为助催化剂,氧气(环境空气)为终端氧化剂,可见光照射底物溶液,以优异的收率生成所需的腈.该反应涉及两种不同的转化:醛和铵盐之间形成亚胺,以及通过空气将形成的亚胺光催化氧化成腈.
Doi:10.1007/s11426-023-1748-4

专利信息

专利号:US-6156922-A
优先权日:1995-12-28
标题 :Method for the synthesis of an aromatic derivative ortho-disubstituted by a halogen atom other than fluorine and by a cyano group
发明人：RUSSELL JAMES; GILBERT LAURENT; MAESTRO JEAN PIERRE
权利人:RHODIA CHIMIE SA
摘要:PCT No. PCT/FR96/02100 Sec. 371 Date Sep. 15, 1998 Sec. 102(e) Date Sep. 15, 1998 PCT Filed Dec. 27, 1996 PCT Pub. No. WO97/24318 PCT Pub. Date Jul. 10, 1997The present invention relates to a method for the synthesis of a halogen substituted aryl nitrile, where the halogens are selected from Cl, Br, or I, by reacting an aryl dihalide with a halogen/fluoride exchange reactant to produce a halogen substituted aryl fluoride which is then reacted with a fluoride/cyanide exchange reactant to produce the halogen substituted aryl nitrile.

专利号:WO-9724318-A1
优先权日:1995-12-28
标题:Method for synthesis of an aromatic derivative substituted by a halogen atom other than fluorine and by a cyano group

专利号:EP-0882012-B1
优先权日:1995-12-28
标题 :Method for synthesis of an aromatic derivative substituted by a halogen atom other than fluorine and by a cyano group

专利号:EP-0882012-A1
优先权日:1995-12-28
标题:Method for synthesis of an aromatic derivative substituted by a halogen atom other than fluorine and by a cyano group

专利号:RU-2146253-C1
优先权日:1995-06-21
标题:Derivatives of 4-phenylaminothazole, methods of their synthesis and pharmaceutical composition