CAS: 99-59-2; 2-Methoxy-5-Nitroaniline

上下游产品

CAS号119-27-7 2,4-二硝基苯甲醚 | CAS号90-04-0 邻氨基苯甲醚 | CAS号136833-44-8 2-nitro-4-amino... | CAS号100-17-4 4-硝基苯甲醚 | CAS号93-26-5 2-乙酰氨基苯甲醚 | CAS号59263-62-6 2-METHOXY-5-NIT... | CAS号10496-75-0 2-甲氧基-5-硝基苯甲腈 | CAS号89-41-8 4-甲氧基-3-硝基苯甲酸 | CAS号100-66-3 苯甲醚 | CAS号97-00-7 1-氯-2,4-二硝基苯 | CAS号455-93-6 2-氟-4-硝基苯甲醚 | CAS号59741-17-2 2-甲氧基-5-异氰酸硝基苯 | CAS号4920-79-0 2-氯-4-硝基苯甲醚 | CAS号149686-06-6 2-Methoxy-5-nit... | CAS号26021-21-6 N-[2-[(2-Bromo-... | CAS号19056-41-8 3-溴-4-甲氧基苯胺 | CAS号119-27-7 2,4-二硝基苯甲醚 | CAS号71793-51-6 2-异硫代氰酰基-1-甲氧基-4-硝基苯 | CAS号636-93-1 5-硝基愈创木酚 | CAS号5197-28-4 2-溴-4-硝基苯甲醚

4-甲氧基-3-硝基苯甲酸置于ammonium Sulfide,硝酸体系中,化学反应生成 2-氨基-4-硝基苯甲醚
参考文献:Adrenocortical Dysfunction Following Etomidate Induction In Emergency Department Patients
标题:Adrenocortical Dysfunction Following Etomidate Induction In Emergency Department Patients
摘要:Abstract. Objective: To Assess Adrenocortical Function Following Intravenous Etomidate Use In Emergency Department (Ed) Patients Requiring Intubation. Methods: This Was A Prospective,Randomized,Controlled Trial Of Consecutive Patients Presenting To The Ed Requiring Intubation. Patients Were Randomized To Receive A Single Bolus Induction Dose Of Either 0.05‐0.1 Mg/kg Midazolam (Control Group) Or 0.3 Mg/kg Etomidate (Etomidate Group) During A Standardized Rapid‐sequence Intubation (Rsi) With Succinylcholine. The Primary Outcome Variable Was Adrenocortical Function At 4,12,And 24 Hours Post‐induction As Assessed By Measured Serum Cortisol Response To Exogenous Cosyntropin (Cosyntropin Stimulation Test,Cst). Fisher'S Exact Test Was Used To Compare Cst Results Between Groups. Results: Thirty‐one Patients Were Enrolled: 8 Control,10 Etomidate,And 13 Excluded From Analysis For Either Incomplete Data Or Steroid Use During The Study Period. The 4‐hour Cst Results Were Significantly Different Between Study Groups,With A Normal Response In 100% Of Control Patients Vs 30% Of Etomidate Patients (P = 0.004). The 12‐ And 24‐hour Csts Did Not Differ Significantly Between Groups: Normal Cst In 100% Of Control Patients At 12 And 24 Hours Vs 100% And 90% Among Etomidate Patients At 12 And 24 Hours,Respectively (P = 1.0 At 12 And 24 Hours). Measured Cortisol Levels Of Patients With Abnormal Csts Remained Within Normal Laboratory Reference Ranges. Conclusion: Use Of Etomidate In Ed Patients Requiring Rsi Results In Adrenocortical Dysfunction. However,Cortisol Levels Remain Within Normal Laboratory Levels During This Period Of Dysfunction. Adrenocortical Dysfunction Appears To Resolve Within 12 Hours Of A Single Bolus Dose Of 0.3 Mg/kg Etomidate.
DOI:10.1111/j.1553-2712.2001.Tb00537.X

专利信息

专利号:US-10799441-B2
优先权日:2011-06-06
标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
发明人：LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

专利号:US-4719053-A
优先权日:1980-08-01
标题 :Beta-chloroethylsulfonylmethyl-benzoic halides as intermediates
发明人：SCHLAEFER LUDWIG; HAEHNLE REINHARD
权利人:HOECHST AG
摘要:New beta -chloroethylsuflonylmethyl-benzoic acid halides which can serve as fibre-reactive anchors for thesynthesis of novel organic, water-soluble compounds, preferably dyestuffs, having fibre-reactive and fibre-finishing properties, such as preferably dyestuff properties, and containing, as a fibre-reactive group, one or two beta -chloroethylsufonylmethylbenzoic acid amide groups. For the synthesis of these novel fibre-finishing compounds, said new beta -chloroethylsulfonylmethyl-benzoic acid halide compounds are reacted with an organic, water-soluble compound having fibre-finishing properties and continuing one or two amino groups. Also precursors of the fibre-finishing, fibre-reactive compounds, containing said beta -chloroethylsulfonylmethyl-benzxoic acid amid grouping, can be employed for their synthesis. The novel fibre-finishing compounds can be applied onto suitable fibre materials, such as especially cellulose fibre material and natural or synthetic polyamide fibre materials, and fixed on these fibre materials in a manner similar to application and fixation methods usual in the technique for fibre-reactive compounds. The fibre-finished material, such as dyed material, shows very good wet fastnesses.

专利号:US-4118384-A
优先权日:1976-02-21
标题 :Process for preparation of azo dyestuffs by coupling in presence of aromatic sulphonic acid-formaldehyde reaction product
发明人：MOLLS HANS-HEINZ; SCHIWY WILLY; HORNLE REINHOLD; NEBELING REINHARD
权利人:BAYER AG
摘要:Dyestuff dispersions and dyestuff solutions free from salt or at least having a low salt content are obtained in that the diazotization is carried out with addition of free dispersing agent acid to which, after the synthesis, either no basic agents are added or basic agents are added only up to a pH value of 3. The disclosed process gives dyestuff compositions of low salt content and results in readily dispersible dyestuffs when water insoluble dyestuffs are prepared and stable solutions when water soluble dyestuffs are prepared. The process is widely applicable and chemical constitution of the dyestuffs is conventional.

专利号:US-2007072894-A1
优先权日:2005-03-24
标题:Synthesis of pyrroloquinoline quinone (PQQ)
发明人：KEMPF J V; GOPAL DAMODARA; STALZER WALTER
权利人:KEMPF J V; GOPAL DAMODARA; STALZER WALTER
摘要:The invention relates to a novel nine step process for synthesizing PQQ (methoxatin). This process is efficient and reliably provides PQQ in excellent purity and high yield.

专利号:US-4035350-A
优先权日:1975-01-30
标 题:Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid
发明人：LANDLER JOSEF; WORFEL ERHARD
权利人:HOECHST AG
摘要:A new and very advantageous Process had been found for the preparation of azo dyestuffs by diazotation and coupling in which the synthesis is carried out without the hitherto usual addition of an acid, with the proviso that at least one of the diazo and coupling components contains at least one acid group. Besides the saving of reaction material and subsequently of alkali for neutralization of the reaction medium and isolation of the dyestuff, highly concentrated solutions of the dyestuff and salt-free or practically salt-free dyestuffs can be obtained, and waste-water is no longer charged with big amounts of salts.

专利号:US-7745490-B2
优先权日:2004-05-12
标题 :Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies
发明人：SNOW ALAN D; NGUYEN BETH P; LAKE THOMAS P; CASTILLO GERARDO M; WEIGELE MANFRED
权利人:PROTEOTECH INC
摘要:Substituted n-aryl benzamides, related compounds and their pharmaceutically acceptable derivatives, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided.