CAS: 951-82-6; 3,4,5-Trimethoxyphenylacetic Acid

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CAS号13338-63-1 3,4,5-三甲氧基苯乙腈 | CAS号91134-18-8 (3,4,5-trimetho... | CAS号3840-31-1 3,4,5-三甲氧基苯甲醇 | CAS号1916-07-0 3,4,5-三甲氧基苯甲酸甲酯 | CAS号3840-30-0 3,4,5-三甲氧基苄氯 | CAS号21852-50-6 3,4,5-三甲氧基苄溴 | CAS号91248-14-5 2-(3,4,5-trimet... | CAS号2989-06-2 3,4,5-TRIMETHOX... | CAS号61404-52-2 Benzenepropanoi... | CAS号124-38-9 二氧化碳 | CAS号37785-48-1 3,4,5-三甲氧基苄醇 | CAS号324519-54-2 α-甲苯磺酰-(3,4,5-三... | CAS号50987-66-1 5-(2-chloroethy... | CAS号195202-06-3 (R/s)-2-(3,4,5-... | CAS号2989-06-2 3,4,5-TRIMETHOX... | CAS号29511-09-9 2-(3,4,5-trihyd... | CAS号195202-08-5 (S)-2-(3,4,5-三甲... | CAS号1885-35-4 3,4,5-三甲氧基苯甲腈 | CAS号61349-11-9 脱甲基5'-甲氧基月桂氨酸 | CAS号101-30-4 4,5-Dihydro-2-[...

(3,4,5-三甲氧基苯基)乙醇腈置于盐酸,溶剂黄146,Tin(Ll) Chloride体系中,化学反应生成 3,4,5-三甲氧基苯乙酸
参考文献:The Synthesis Of Dl-Colchinol Methyl Ether1,2
标题:The Synthesis Of Dl-Colchinol Methyl Ether1,2
摘要:
DOI:10.1021/ja01148A005

专利信息

专利号:US-9573934-B2
优先权日:2011-01-26
标题 :Methods and compositions for the synthesis of multimerizing agents
发明人：LI FENG; WANG YIHAN
权利人:ARIAD PHARMA INC
摘要:The invention features methods and compositions for the synthesis of multimerizing agents.

专利号:US-6177572-B1
优先权日:1997-08-20
标题 :Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use
发明人：WANG FENGJIANG
权利人:SEPRACOR INC
摘要:Methods for preparing benzoxazoles and benzothiazoles on solid supports. Substituted benzothiazoles and benzoxazoles, libraries of the compounds, and methods of using the compounds are also disclosed.

专利号:US-5942632-A
优先权日:1995-07-28
标题:Solid phase synthesis method
发明人：WANG GARY T
权利人:ABBOTT LAB
摘要:A solid phase synthesis method and intermediates useful in the process are disclosed for the preparation of diamino diol and diamino alcohol inhibitors of HIV protease.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-8853228-B2
优先权日:2007-06-04
标 题:Heterocyclic analogs of propargyl-linked inhibitors of dihydrofolate reductase
发明人：ANDERSON AMY C; WRIGHT DENNIS L; FREY KATHLEEN MARY; PAULSEN JANET LEIGH; SCOCCHERA ERIC WILLIAM; VISWANATHAN KISHORE
权利人:ANDERSON AMY C; WRIGHT DENNIS L; FREY KATHLEEN MARY; PAULSEN JANET LEIGH; SCOCCHERA ERIC WILLIAM; VISWANATHAN KISHORE; UNIV CONNECTICUT
摘要:The compositions and methods described herein disclose the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as Bacillus anthracis and methicillin-resistant Staphylococcus aureus , fungi such as Candida glabrata, Candida albicans and Cryptococcus neoformans and protozoa such as Cryptosporidium hominis and Toxoplasma gondii . These compounds and other similar compounds are also potent against the mammalian enzyme and may be useful as anti-cancer therapeutics.

专利号:US-8426432-B2
优先权日:2007-06-04
标 题 :Inhibitors of dihydrofolate reductase with antibacterial antiprotozoal, antifungal and anticancer properties
发明人：ANDERSON AMY C; WRIGHT DENNIS L; PELPHREY PHILLIP M; JOSKA TAMMY M; BOLSTAD ERIN S D; BOLSTAD DAVID B; POPOV VELJKO
权利人:ANDERSON AMY C; WRIGHT DENNIS L; PELPHREY PHILLIP M; JOSKA TAMMY M; BOLSTAD ERIN S D; BOLSTAD DAVID B; POPOV VELJKO; UNIV CONNECTICUT
摘要:The compositions and methods described herein discloses the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as Bacillus anthracis and methicillin-resistant Staphylococcus aureus , fungi such as Candida glabrata, Candida albicans and Cryptococcus neoformans and protozoa such as Cryptosporidium hominis and Toxoplasma gondii . These compounds and other similar compounds are also potent against the mammalian enzyme and may be useful as anti-cancer therapeutics.