CAS: 99-32-1; 4-Oxo-4H-Pyran-2,6-Dicarboxylic Acid

该化合物是一种热循环有机化合物,在化学和药学研究的协调方面有显著应用,其硬性皮兰骨干和双箱式聚变组具有很强的发泡特性,有助于在分析和催化过程中结合金属离子;该化合物的结构特征也有助于其作为合成生物活性衍生物的前体发挥作用; 切利多尼酸在标准条件下具有稳定性,并且可溶解于极地溶剂,便于其在实验室环境中使用; 它在形成复杂物和潜在药理学相关性方面的多功能性突出其在化学和生物医学研究中的价值.

结构式图片

相似化合物

6003-94-7 499-05-8 725-92-8

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号95-92-1 草酸二乙酯 | CAS号67-64-1 丙酮 | CAS号68854-18-2 三氧代庚二酸二乙酯 | CAS号105-50-0 丙酮二羧酸二乙酯 | CAS号7647-01-0 盐酸 | CAS号1120-93-0 4H-Pyran-4-thione | CAS号1120-94-1 4H-Thiopyran-4-... | CAS号4722-94-5 4-氯吡啶-2,6-二羧酸 | CAS号5371-70-0 4-氯-2,6-二吡啶甲酸甲酯 | CAS号293294-71-0 4-Chloro-6-(Met... | CAS号502-50-1 4-酮庚二酸 | CAS号499-05-8 靠曼酸 | CAS号499-51-4 4-羟基吡啶-2,6-二甲酸 | CAS号19872-91-4 4-羟基-2,6-吡啶二甲酸二甲酯 | CAS号79-49-2 五溴丙酮

合成工艺路线路线简述

  • 合成目标产物 Chelidonic Acid 主要起始原料 Diethyl Oxalate And Acetone
  • (文献来源)合成步骤主要原料 Diethyl Oxalate 和 Acetone
Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 白屈菜酸
参考文献:Haitinger; Lieben,Monatshefte Fur Chemie,1884,Vol. 5,P. 363
标题:Haitinger; Lieben,Monatshefte Fur Chemie,1884,Vol. 5,P. 363

海关参考信息

专利信息


专利号:US-11078073-B2
优先权日:2015-02-23
标 题:Self-processing synthesis of hybrid nanostructures
发明人:YERUSHALMI ROIE; PALTIEL YOSSEF; PINCHAS-HAZUT ORI; WAICHMAN SHARON; ZIV AMIR; YOCHELIS SHIRA
权利人:YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD
摘要:Provided is a self-processing synthesis of hybrid nanostructures, novel nanostructures and uses thereof in the construction of electronic and optoelectronic devices.

专利号:US-2021107859-A1
优先权日:2018-04-06
标题 :A process for the synthesis of carbon labeled organic compounds
发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

专利号:US-2013267680-A1
优先权日:2010-09-15
标题:Total chemical synthesis of ubiquitin, ubiquitin mutants and derivatives thereof
发明人:OVAA HUIB; EL OUALID FARID; MERKX REMCO NICOLAAS SEBASTIAAN MICHEL
权利人:OVAA HUIB; EL OUALID FARID; MERKX REMCO NICOLAAS SEBASTIAAN MICHEL; STICHTING HET NL KANKERINST
摘要:The present invention relates to the field of total chemical synthesis of ubiquitin and related peptides. More in particular, a method is provided of solid phase synthesis of ubiquitin, ubiquitin mutants and derivatives thereof. It was the object of the present invention to provide an approach for the total chemical synthesis of ubuiqitin, which allows for the chemical synthesis of virtually any Ub mutant and giving high overall efficiency and purity. The present inventors have surprisingly found that this object can be realized with a method relying on incorporation of special amino acid building blocks. This approach was found to allow for exceptionally high yields of up to 14% and to provide an synthetic entry into virtually any ubiquitin derivative.

专利号:US-6815214-B2
优先权日:2000-12-29
标 题 :Pharmaceutical uses and synthesis of diketopiperazines
发明人:BOYCE JIM P; HOWBERT J JEFFRY; TABONE JOHN C
权利人:CELLTECH R & D INC
摘要:The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-α, TNF-β and also apoptosis.

专利号:US-12209023-B2
优先权日:2017-01-25
标题:Low temperature, high yield synthesis of hydrogen terminated highly porous amorphous silicon, and nanomaterials and composites from Zintl phases
发明人:WAGNER MICHAEL J; BANEK NATHAN A
权利人:UNIV GEORGE WASHINGTON
摘要:The present disclosure relates to an improved process for the synthesis of hydrogen terminated silicon from Zintl phases. The hydrogen terminated silicon is useful, for example, as explosives, chemical and biochemical sensors, optoelectronic materials and Li-ion battery anode ion storage materials. The present disclosure also relates to an improved process for the synthesis of nanomaterials and composites from Zintl phases. The nanomaterials and composites are useful, for example, as ion storage materials.

专利号:US-9242925-B2
优先权日:2011-08-29
标题:Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction
发明人:JUGE SYLVAIN; BAYARDON JEROME; REMOND EMMANUELLE; ONDEL-EYMIN MARIE-JOELLE
权利人:JUGE SYLVAIN; BAYARDON JEROME; REMOND EMMANUELLE; ONDEL-EYMIN MARIE-JOELLE; CENTRE NAT RECH SCIENT; UNIV BOURGOGNE
摘要:The γ,δ-unsaturated α-amino acids of general formula (I). Also, a versatile process for the stereospecific synthesis of said compounds of formula (I), involving a Wittig reaction. Further, intermediate products of general formulae (II) and (III), as shown below, which are involved in the synthesis of compounds (I). n n n n n n n n n n n n Compounds of general formula (I) may be useful as therapeutic substances, or as reagents or intermediates for fine chemistry.
西安原生植物工程技术有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.originherb.com
电话: 86-029-88391621👤
📞西安原生植物工程技术有限公司 ⚠️参考联系方式

销售电话:86-029-88391621
邮箱:xianyuansheng@vip.sina.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

地址:陕西西安市开发区沣惠南路枫叶新都市C7B座402室
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
盐城云涛化工有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.yuntao-chem.com
企业联系电话:0515-83090980;13512592619👤
📞盐城云涛化工有限公司 ⚠️参考联系方式
联系人:郭先生 13512592619
电话:0515-83090980;13512592619
手机:13512592619
传真:0515-83090980
邮箱:2838893166@qq.com
通信地址: 江苏省盐城市解放南路239号汇景大厦613室
邮编: 224011
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

地址:江苏省盐城市解放南路239号汇景大厦613室
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
第 1 / 1 页
现货

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Kopp T, Abdel-Tawab M, Khoeiklang M, Mizaikoff B. Development of a Selective Adsorbing Material for Binding of Pyrrolizidine Alkaloids in Herbal Extracts, Based on Molecular Group Imprinting. Planta Med. 2019 Sep;85(13):1107-1113. doi: 10.1055/a-0961-2658. Epub 2019 Aug 5. 5(5):e01586. doi: 10.1016/j.heliyon.2019.e01586.
3: Avdeeva E, Shults E, Rybalova T, Reshetov Y, Porokhova E, Sukhodolo I, Litvinova L, Shupletsova V, Khaziakhmatova O, Khlusov I, Guryev A, Belousov M. Chelidonic Acid and Its Derivatives from Saussurea Controversa: Isolation, Structural Elucidation and Influence on the Osteogenic Differentiation of Multipotent Mesenchymal Stromal Cells In Vitro. Biomolecules. 2019 May 16;9(5):189. doi: 10.3390/biom9050189.
4: Singh DK, Gulati K, Ray A. Effects of chelidonic acid, a secondary plant metabolite, on mast cell degranulation and adaptive immunity in rats. Int Immunopharmacol. 2016 Nov;40:229-234. doi: 10.1016/j.intimp.2016.08.009. Epub 2016 Sep 9. 241(14):1559-67. doi: 10.1177/1535370216642044. Epub 2016 Mar 31.

合成参考文献


摘要:S. Miyamoto and E. Brochmann-Hanssen, J. Pharm. Sci. 51, 552 (1962).
参考文献:10.1007/s004250000470
摘要:Park WJ, Schäfer A, Prinsen E, van Onckelen H, Kang BG, Hertel R. Auxin-induced elongation of short maize coleoptile segments is supported by 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one. Planta. 2001 May;213(1):92–100. doi: 10.1007/s004250000470.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知