CAS: 24100-18-3; 2-Bromo-3-Methoxypyridine

上下游产品

CAS号6602-32-0 2-溴-3-羟基吡啶 | CAS号74-88-4 碘甲烷 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号109-00-2 3-羟基吡啶 | CAS号186581-53-3 重氮甲烷 | CAS号36145-03-6 2,2'-联吡啶-3,3'-二醇 | CAS号144190-35-2 6-(3-hydroxy-1H... | CAS号616-47-7 N-甲基咪唑 | CAS号79491-44-4 2,3-二甲氧基-6-硝基吡啶 | CAS号79491-43-3 2-氨基-6-溴-5-甲氧基吡啶 | CAS号93560-55-5 2-碘-3-甲氧基吡啶 | CAS号24059-89-0 2-腈基-3-甲氧基吡啶 | CAS号7295-76-3 3-甲氧基吡啶 | CAS号52605-97-7 2,3-二甲氧基吡啶

3-羟基吡啶置于sodium Hydroxide,溴,Sodium Methylate体系中,化学反应 25.5H,反应生成2-溴-3-甲氧基吡啶
参考文献:Total Synthesis Of Orellanine
标题:Total Synthesis Of Orellanine
摘要:
Doi:10.1016/s0040-4020(01)87367-1

专利信息

专利号:US-8633182-B2
优先权日:2012-05-30
标题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN
权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-7615634-B2
优先权日:2003-02-10
标题:4-aminopyrimidine-5-one derivatives
发明人：BARTKOVITZ DAVID JOSEPH; CHU XIN-JIE; DING QINGJIE; JIANG NAN; LOVEY ALLEN JOHN; MOLITERNI JOHN ANTHONY; MULLIN JR JOHN GUILFOYLE; VU BINH THANH; WOVKULICH PETER MICHAEL
权利人:HOFFMANN LA ROCHE
摘要:Novel intermediate compounds are disclosed. These compounds are useful in the synthesis of 4-aminopyrimidine-5-one derivatives that inhibit cyclin-dependent kinases, in particular cyclin-dependent kinase 4 (Cdk4). The 4-aminopyrimidine-5-one derivatives and their pharmaceutically acceptable salts have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors.

专利号:CN-116854632-A
优先权日:2023-07-07
标题:Synthesis method and application of large-steric-hindrance heteroatom compound