CAS: 93697-74-6; Pyrazosulfuron-Ethyl

该化合物是一种高效的灭蚁灵,广泛用于稻田选择性除草剂,其化学名称为乙基 5-(4,6-二甲基丙酰胺-2-丙基乙酰氟磺酰氟基)-1-甲基双甲苯甲醚-4-氯苯基甲酸酯)-这种复合作用抑制了乙醇酶合成酶(ALS),该酶是分链氨基酸生物合成中的一种关键酶,导致抑制了杂草生长.它展示了针对广泛各种年度和常年杂草的出色活动,包括套头和宽叶叶类. 丙烯磺酰氟乙基的特点是其应用率低(通常为15-30 g ai/ha),对稻米作物的高度选择性,以及长期残留活动. 其杀草剂表现出良好的系统特性,并且有效前和后发酵. 它的有利环境特征包括土壤迅速退化和对非目标生物毒性低.

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CAS号88398-81-6 乙基 1-甲基-5-胺磺酰基-...

合成工艺路线路线简述

  • 合成目标产物 Pyrazosulfuron-Ethyl 主要起始原料 2-Amino-4,6-Dimethoxypyrimidine And Sulphonyl Diisocyanate
  • 88399-05-7 + 36315-01-2 = 93697-74-6
    反应条件:1.1 Solvents: Acetonitrile
    标题:Preparation Of 5-Pyrazolesulfonyl Chloride Derivatives As Intermediates For N-Pyrazolesulfonyl-N'-Heterocyclylurea Herbicides
    参考文献:Japan]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Synthesis Of Ethyl 5-[(Methoxycarbonyl)Aminosulfonyl]-1-Methylpyrazole-4-Carboxylate By Non-Phosgene Method
    作者:Sun,Xiaohong; Liu,Yuanfa; Jia,Yingqi; Chen,Bang
    参考文献:Huaxue Gongcheng (Xi'An 日期:2005 卷标:33(2) 页码:69-70]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Development And Commercialization Of New Herbicide Pyrazosulfuron-Ethyl
    作者:Yamamoto,Susumu; Suzuki,Fumio; Iwasawa,Yoshihiro; Sato,Toshiaki
    参考文献:Yuki Gosei Kagaku Kyokaishi 日期:1994 卷标:52(1) 页码:19-26]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Solventless Process For Preparing Herbicidal Sulfonylureas
    参考文献:United States]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Method For Reaction Of Methyl Esters With Active Hydrogen-Containing Compounds
    参考文献:Japan]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Pyridinedicarbothioate And Pyrimidinylureidosulfonylpyrazolecarboxylate Herbicide Mixture
    参考文献:Japan]

    = 93697-74-6 [标题:Reaction Conditions
    标题:(Pyrazolylsulfonyl)Ureas
    参考文献:Japan]

    88399-05-7 + 36315-01-2 = 93697-74-6
    反应条件:1.1 Reagents: Dabco Solvents: Dichloromethane; Rt -> 55 °C; 16 H,55 °C; 55 °C -> Rt; 6 H
    标题:A Process For The Preparation Of The Herbicide Pyrazosulfuron Ethyl
    参考文献:India]

    88398-81-6 + 36315-01-2 = 93697-74-6
    反应条件:1.1 Catalysts: Butyl Isocyanate,Dabco Solvents: Xylene1.2 Solvents: 1,2-Dichloroethane
    标题:Synthesis Of Pyrazosulfuron-Ethyl By Non-Phosgene Method
    作者:Liu,Xinhe; Wang,Xueqin; Chen,Hua
    参考文献:Nongyao 日期:2000 卷标:39(12) 页码:14-15]

    159709-60-1 + 36315-01-2 = 93697-74-6
    反应条件:1.1 Rt -> Reflux; 7 H,Reflux; Reflux -> 20 °C
    标题:Study On Preparation Of Herbicide Pyrazosulfuron
    作者:Li,Peng; Liu,Feng-Ying; Li,Hui-Qin
    参考文献:Jingxi Yu Zhuanyong Huaxuepin 日期:2006 卷标:14(15) 页码:11-12]

    917-61-3 + 88398-82-7 + 36315-01-2 = 93697-74-6
    反应条件:1.1 Solvents: Benzene,Pyridine; 3 H; 2 H,40 - 45 °C1.2 4 H,40 - 45 °C1.3 Reagents: Sulfuric Acid Solvents: Water; Ph 4
    标题:Synthesis Of Pyrazosulfuron-Ethyl
    作者:Wang,Baoyu; Xu,Jingzhe; Jiang,Rishan
    参考文献:Yanbian Daxue Xuebao 日期:2002 卷标:28(3) 页码:176-179]

    88399-04-6 + 36315-01-2 = 93697-74-6 [标题:Reaction Conditions
    标题:Pyrazolesulfonylurea Derivatives
    参考文献:Japan]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Process For The Preparation Of N-Pyrazolylsulfonyl-N'-Dimethoxypyrimidinylureas
    参考文献:European Patent Organization]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Pyrimidinyl(Pyrazolesulfonyl)Urea Derivatives
    参考文献:Japan]

    = 93697-74-6 [标题:Reaction Conditions
    标题:Pyrazolesulfonylurea Derivatives
    参考文献:Japan
2-氨基-4,6-二甲氧基嘧啶,异氰酸砜 以 乙腈 作为反应溶剂,化学反应生成 吡嘧磺隆
参考文献:Pyrazolesulfonylurea Derivatives,Preparation Thereof,Herbicide
标题:Pyrazolesulfonylurea Derivatives,Preparation Thereof,Herbicide
摘要:揭示了一种新型吡唑磺酰脲衍生物,其化学式表示为(i),其制备方法,含有该衍生物作为活性成分的除草剂,以及使用该衍生物的除草方法.##str1##(其中a,B,C,D,X,Y和z的定义如规范中所述).

海关参考信息

专利信息


专利号:US-7583805-B2
优先权日:2004-02-12
标题:Late reverberation-based synthesis of auditory scenes
发明人:BAUMGARTE FRANK; FALLER CHRISTOF
权利人:AGERE SYSTEMS INC
摘要:A scheme for stereo and multi-channel synthesis of inter-channel correlation (ICC) (normalized cross-correlation) cues for parametric stereo and multi-channel coding. The scheme synthesizes ICC cues such that they approximate those of the original. For that purpose, diffuse audio channels are generated and mixed with the transmitted combined (e.g., sum) signal(s). The diffuse audio channels are preferably generated using relatively long filters with exponentially decaying Gaussian impulse responses. Such impulse responses generate diffuse sound similar to late reverberation. An alternative implementation for reduced computational complexity is proposed, where inter-channel level difference (ICLD), inter-channel time difference (ICTD), and ICC synthesis are all carried out in the domain of a single short-time Fourier transform (STFT), including the filtering for diffuse sound generation.

专利号:US-5883221-A
优先权日:1996-11-12
标题:Synthesis of polybenzoxasole and polybenzothiazole precursors
发明人:SEZI RECAI; KUEHN EBERHARD; AHNE HELLMUT; KOCMAN SUELEYMAN
权利人:SIEMENS AG
摘要:In a method of synthesis of polybenzoxazole and polybenzothiazole precursors, a dicarboxylic acid or a dicarboxylaic acid ester is reacted with a bis-o-aminophenol or bis-o-aminothiophenol in a suitable solvent in the presence of an activating reagent having the following structure: ##STR1##

专利号:US-9981949-B2
优先权日:2008-12-01
标题 :Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
发明人:AKIREDDY SRINIVASA RAO; BHATTI BALWINDER SINGH; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; MILLER CRAIG HARRISON; MITCHENER JR JOSEPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT
权利人:OYSTER POINT PHARMA INC
摘要:The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.

专利号:US-8604191-B2
优先权日:2008-12-01
标 题:Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3YLVINYL)pyrimidine
发明人:AKIREDDY SRINIVASA RAO; BHATTI BALWINDER SINGH; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; MILLER CRAIG HARRISON; MITCHENER JR JOSEPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT
权利人:AKIREDDY SRINIVASA RAO; BHATTI BALWINDER SINGH; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; MILLER CRAIG HARRISON; MITCHENER JR JOSEPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT; TARGACEPT INC
摘要:The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-yl)pyrimidine, novel salt forms, and novel polymorphic forms of these salts.

专利号:WO-2020261298-A1
优先权日:2019-06-28
标 题 :Nanodiamond embedded biomolecular glass from egg and method of production of the same
发明人:SEKHAR RAY SIRSENDU; PRATAP TRIPATHY SOUMYA
权利人:SEKHAR RAY SIRSENDU
摘要:The present invention provides glass or nanodiamond embedded biomolecular glass derived from egg white or egg yolk. The said glass or nanodiamond is prepared through the route of synthesis of glass from biomass, wherein egg white or yolks are used as precursor of glass containing nanodiamond in it. Also the invention also provides methods for co-production of glass ceramic and nanodiamond in a one pot route of synthesis thereby reducing a lot of cost and equipment need in separate process. The present invention glass or nanodiamonds are very useful in various field of application including healthcare due to significant biocompatibility of nanodiamonds.

专利号:US-H409-H
优先权日:1987-06-29
标题 :Synthesis of cadmium sulfide using the laser-induced reaction of dialkylcadmium and organosulfur compounds
摘要:Cadmium sulfide is formed successfully from the laser-induced chemical reion between a first reactant of a dialkylcadmium and a second reactant of a dialkylsulfide. Infrared laser radiation in the range of 10.4 or 9.4 micrometers is provided by a continuous-wave CO 2 laser. In single line operation, output powers between 10 and 150 watts/centimeters square (W/cm 2 ) are obtained by variation of the CO 2 -N 2 -He gas mixture in the laser. The process procedure and sample handling is accomplished using standard vacuum line techniques. The irradiation of dimethylsulfide at R(18) of (00°1-10°0) for 5 seconds at 100 W/cm 2 produced the products methane, ethane, and sulfur. A mixture of a dialkylsulfide (CH 3 ) 2 S, and a dialkylcadmium (CH 3 ) 2 Cd is irradiated at R(18) of (00°1-10°0), 979 cm -1 for a total of 5 seconds at 100 W/cm 2 to form CdS on the windows of the reaction cell. A higher yield of CdS is obtained when the sensitizer SR 6 is added to the mixture of the reactants. Excitation of the mixture occurs using P(20) of (00°1-10° 0) at 944 cm -1 for 5 seconds at 100 W/cm 2 . The representative torr pressures of the reactants are for (CH 3 ) 2 Cd 33 torr combined with (CH 3 ) 2 S to total 100 torr pressure prior to irradiation. The efficiency when SF 6 (6 torr) plus (CH 3 ) 2 Cd (22.4 torr) is combined with 54.5 torr of (CH 3 ) 2 S and irradiated is improved.
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主要参考文献

Luo XW, Zhang DY, Zhu TH, Zhou XG, Peng J, Zhang SB, Liu Y. Adaptation mechanism and tolerance of Rhodopseudomonas palustris PSB-S under pyrazosulfuron-ethyl stress. BMC Microbiol. 2018 Dec 7;18(1):207. doi: 10.1186/s12866-018-1361-y.

合成参考文献


摘要:Japan Pesticide Information., (55)(17), 1989
参考文献:10.1107/s1600536810031740
摘要:Xie RL, Zhang T, Cao AC, Mei XD. 4-(4-Chloro-5-methyl-3-trifluoro-meth-yl-1H-pyrazol-1-yl)-6-(prop-2-ynyl-oxy)pyrimidine. Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 18;66(Pt 9):o2307.
参考文献:10.1002/ps.786
摘要:Kuk YI, Kim KH, Kwon OD, Lee DJ, Burgos NR, Jung S, Guh JO. Cross‐resistance pattern and alternative herbicides for Cyperus difformis resistant to sulfonylurea herbicides in Korea. Pest Management Science. 2003 Nov 03;60(1):85–94. doi: 10.1002/ps.786.
参考文献:10.1007/s11103-006-0058-z
摘要:Pan G, Zhang X, Liu K, Zhang J, Wu X, Zhu J, Tu J. Map-based cloning of a novel rice cytochrome P450 gene CYP81A6 that confers resistance to two different classes of herbicides. Plant Mol Biol. 2006 Aug;61(6):933–43. doi: 10.1007/s11103-006-0058-z.
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