CAS: 126918-17-0; (2R)-1-(2,4-Difluorophenyl)-2-((Tetrahydro-2H-Pyran-2-yl)Oxy)Propan-1-One

相似化合物

126918-16-9 241479-69-6 939439-00-6

上下游产品

(R)-1-(2,4-二氟苯基)-2-羟基丙烷-1-酮 (R)-1-(2,4-Difluorophenyl)-2-Hydroxypropan-1-One 126918-16-9
2',4'-Difluoro-(S)-2-Hydroxypropiophenone 126918-14-7
(2R)-1-(2,4-Difluorophenyl)-2-Trimethylsilyloxypropan-1-One 161457-73-4
(S)-2-(P-Toluenesulfonyloxy)-2',4'-Difluoropropiophenone 126918-15-8

[1-(2,4-Difluorophenyl)-1-Oxopropan-2-Yl] Acetate置于4-甲基苯磺酸吡啶体系中,用 水 用作溶剂,化学反应 3.0H,反应生成(2R)-1-(2,4-二氟苯基)-2-[(四氢-2H-吡喃-2-基)氧基]-1-丙酮
参考文献:抗真菌剂sch 42427 / Sm 9164的制备:色谱分离度和通过酶促制备手性α-羟基芳基酮的全不对称合成
标题:抗真菌剂sch 42427 / Sm 9164的制备:色谱分离度和通过酶促制备手性α-羟基芳基酮的全不对称合成
摘要:描述了通过其对映异构体的大规模色谱分离或通过出色的对映体过量(ee S)的关键手性中间体α-羟基芳基酮5的酶促合成来制备手性唑抗真菌剂sch 42427 / Sm 9164(1)的有效方法.
Doi:10.1016/0040-4039(95)02234-1

专利信息

专利号:US-6133485-A
优先权日:1998-04-15
标 题:Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols
发明人：SINGH INDER PAL; SIDHU INDERJIT; PALAK BHUPINDER; MICETICH RONALD G
权利人:SYNPHAR LAB INC; TAIHO PHARMACEUTICALS CO LTD
摘要:The asymmetric production of pure diastereomeric (2R,3R), (2R,3S), (2S,3R) and (2S,3S)-2-aryl-1-substituted butan-2,3-diols from the derivatives of lactic acid.

专利号:WO-9952840-A1
优先权日:1998-04-15
标题 :Asymmetric synthesis of 2-aryl-1-substituted butan-2,3-diols

专利号:EP-1071640-B1
优先权日:1998-04-15
标题 :Asymmetric synthesis of 2-aryl-1-substituted butan-2,3-diols

专利号:EP-1071640-A1
优先权日:1998-04-15
标题:Asymmetric synthesis of 2-aryl-1-substituted butan-2,3-diols

专利号:RU-2039050-C1
优先权日:1989-09-26
标 题:Derivatives of 1,2,4-triazole, optically inert or containing r- or s-configuration at c-2 and c-3 asymmetric centers, or their salts showing fungicide activity, and a method of their synthesis