CAS: 127-63-9; Sulfonyldibenzene

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CAS号139-66-2 苯硫醚 | CAS号80-07-9 4,4'-二氯二苯砜 | CAS号38980-51-7 2-Chlorophenyl ... | CAS号38980-69-7 1-chloro-3-(4-c... | CAS号618-41-7 苯亚磺酸 | CAS号945-51-7 二苯基亚砜 | CAS号873-55-2 苯亚磺酸钠 | CAS号98-80-6 苯硼酸 | CAS号98-09-9 苯磺酰氯 | CAS号4096-20-2 N-苯基哌啶 | CAS号3074-43-9 1-甲基-4-苯基哌嗪 | CAS号2217-81-4 二苯基二氯化硒 | CAS号139-66-2 苯硫醚 | CAS号92-52-4 联苯 | CAS号108-98-5 硫酚 | CAS号882-33-7 二苯二硫醚 | CAS号618-41-7 苯亚磺酸 | CAS号1829-40-9 六苯基二硅氧烷 | CAS号1048-08-4 四苯基硅烷

苯磺酰肼置于2C2H3O2(1-)*c26H30B10P2*cu(2+)体系中,用 甲苯 用作溶剂,化学反应 3.0H,以92%的收率获得二苯砜
参考文献:一种二芳基砜类化合物的合成方法
标题:一种二芳基砜类化合物的合成方法
摘要:本发明涉及一种二芳基砜类化合物的合成方法,其特征在于,该方法为:将铜配合物和芳基磺酰肼溶于有机溶剂,以空气为氧化剂,室温反应,分离纯化,即得相应二芳基砜类化合物,其中,铜配合物和芳基磺酰肼的摩尔比为(0.01‑0.03):1.0,所述的反应时间为2‑5H.与现有技术相比,本发明合成工艺具有非常好的选择性和较高产率,反应中的催化剂铜配合物在室温条件下可催化芳基磺酰肼的自身偶联合成二芳基砜类化合物,该反应具有条件温和简单,底物范围广,产物分离便捷,反应效率高等特点.

专利信息

专利号:US-2024287520-A1
优先权日:2021-06-30
标题:Method for synthesis of linkage modified oligomeric compounds
发明人：RODRIGUEZ ANDREW A
权利人:IONIS PHARMACEUTICALS INC
摘要:The present disclosure provides methods of synthesizing modified oligonucletodies and oligomeric compounds (including oligomeric compounds that are antisense agents or portions thereof) comprising a modified oligonucleotide having at least one modified internucleoside linking group. In certain embodiments, the present disclosure provides stabilized formulations of certain sulfonyl azides for use in the synthesis of olignonucleotides comprising one or more sulfonyl phosphoramidate linkages. Some embodiments provide stabilized compositions of high energy reagents that may be used in the synthesis of modified oligonucleotides, allowing for safe process scale preparation thereof.

专利号:WO-2024013633-A1
优先权日:2022-07-11
标 题 :Process for the synthesis of vitamin k2
发明人：SHASTRI MAYANK; BAIKAR MRUNALI H; VORA PARIN K; BNS RAJU
权利人:SYNERGIA LIFE SCIENCES PVT LTD
摘要:The present disclosure relates to the synthesis of Vitamin K2 bearing varying prenyl side chains. The synthesis comprises the reaction of phenyl sulfone of tert-butyl dimethyl silyl (TBDMS) protected mono prenyl menadiol with prenyl halides bearing varying prenyl units in the presence of the phase transfer catalyst followed by reductive desulphonation to yield TBDMS ether of Vitamin K2. The TBDMS ether is then oxidized in the presence of chromium trioxide and periodic acid to yield the corresponding Vitamin K2.

专利号:US-2025188046-A1
优先权日:2023-12-08
标题:Ultrafast flow synthesis of functionalized sulfonyl fluorides and subsequent sufex connections via lithiated chemistry
发明人：KIM DONG-PYO; KANG JI-HO
权利人:POSTECH RES & BUSINESS DEV FOUND
摘要:Disclosed are ultrafast flow synthesis of functionalized sulfonyl fluorides and subsequent SuFEx connections via lithiated chemistry. In detail, a method of synthesizing an ortho-functionalized benzenesulfonyl fluoride derivative, the method comprises (a) reacting a benzenesulfonyl fluoride derivative represented by structural formula 1 with an organolithium represented by structural formula 2, thus synthesizing an intermediate represented by structural formula 3 in reaction scheme 1 and (b) reacting the intermediate with an electrophile, thus synthesizing a compound represented by structural formula 4 or a compound represented by structural formula 4′. The present disclosure enables the synthesis of several functionalized sulfonyl fluorides within a few seconds under mild temperature conditions in addition to the chemistry of Sulfonyl Fluoride Exchange (SuFEx), which is a next-generation click chemistry, so that sulfonyl fluoride, the main reactant of the SuFEx reaction, can be efficiently secured.

专利号:US-2024368099-A1
优先权日:2022-01-18
标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes
发明人：SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS
权利人:HENKEL AG & CO KGAA
摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.

专利号:US-10731001-B2
优先权日:2018-11-09
标 题 :Method for the recovery of compounds deriving from the synthesis of poly aryl ether ketone polymers
发明人：SCHON STEVEN GABRIEL; GODDARD ANDREW RICHARD; JOUANNEAU JULIEN
权利人:ARKEMA FRANCE
摘要:A method for treating a shear-thinning residue composition deriving from the synthesis of an aryl ether ketone, the residue composition including a liquid fraction and solid residues, the method including the steps of: passing said shear-thinning residue composition through a shear-generating evaporating device, between a rotating part and a stationary part; and recovering a condensed liquid fraction and separately recover concentrated solid residues.

专利号:US-10973847-B2
优先权日:2017-06-30
标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof
发明人：JOHNSON JEREMIAH A; GOLDER MATTHEW R
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.