CAS: 2674-34-2; 1,4-Dibromo-2,5-Dimethoxybenzene

上下游产品

CAS号150-78-7 对苯二甲醚 | CAS号14753-51-6 2,5-二溴对苯二酚 | CAS号74-88-4 碘甲烷 | CAS号150-76-5 4-甲氧基苯酚(MEHQ) | CAS号77-78-1 硫酸二甲酯 | CAS号7377-91-5 2,3,6-tribromo-... | CAS号123-31-9 对苯二酚 | CAS号106-51-4 苯醌 | CAS号7726-95-6 溴素 | CAS号35458-39-0 4-溴-2,5-二甲氧基苯甲酸 | CAS号19403-94-2 1,2,4,5-tetrabr... | CAS号233753-19-0 2,5-双[3-(N,N-二乙... | CAS号31558-41-5 4-溴-2,5-二甲氧基苯甲醛 | CAS号844-51-9 2,5-二苯基-1,4-苯醌 | CAS号7310-97-6 2,5-二甲氧基苯-1,4-二甲醛 | CAS号14753-51-6 2,5-二溴对苯二酚 | CAS号74029-40-6 1,4-二乙炔基-2,5-二甲氧基苯 | CAS号75670-41-6 9,10-dimethoxy-... | CAS号87050-61-1 (4-bromo-2,5-di...

对苯二甲醚置于氢溴酸,双氧水体系中,用 甲醇 用作溶剂,以99%的收率获得1,4-二溴-2,5-二甲氧基苯
参考文献:用氢卤酸/ H 2 O 2(或tbhp)简单实用地卤代芳烃,烯烃和炔烃
标题:用氢卤酸/ H 2 O 2(或tbhp)简单实用地卤代芳烃,烯烃和炔烃
摘要:提出了使用过氧化氢水溶液(34%)或叔丁基氢过氧化物(70%)和氢卤酸的组合物来卤代芳烃的简单方案.涉及原位产生正卤素试剂的类似的氧卤化方法可用于由烯烃制备邻位的反式-二溴代烷烃和二氯烷烃.烯烃与盐酸和氢溴酸的组合与过氧化氢的反应得到了1-溴2-氯烷烃和1,2-二溴烷烃的混合物.也有类似条件下炔烃的氧化溴化.
Doi:10.1016/s0040-4020(99)00628-6

专利信息

专利号:US-8716532-B2
优先权日:2009-03-27
标 题:One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation
发明人：SHARMA ABHISHEK; SINHA ARUN KUMAR; KUMAR RAKESH; SHARMA NAINA
权利人:SHARMA ABHISHEK; SINHA ARUN KUMAR; KUMAR RAKESH; SHARMA NAINA; COUNCIL SCIENT IND RES
摘要:The present invention provides a method for the preparation of some novel multiconjugated 2- or 4-hydroxy substituted stilbenes. The method provides one pot multicomponent approach wherein 3-4 step reaction sequences viz. condensation, decarboxylation and Heck coupling occur simultaneously which results in an enhanced yield of desired products and reduced reaction times.

专利号:US-2012165567-A1
优先权日:2009-03-27
标 题 :One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation

专利号:WO-2010113005-A2
优先权日:2009-03-27
标题 :One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation

专利号:EP-2118111-B1
优先权日:2007-02-06
标题 :2-amin0-5, 7-dihydr0-6h- pyrrolo [3, 4-d] pyrimidine derivatives as hsp-90 inhibitors for treating cancer
发明人：BENNETT MICHAEL JOHN; ZEHNDER LUKE RAYMOND; NINKOVIC SACHA; KUNG PEI-PEI; MENG JERRY JIALUN; HUANG BUWEN
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, their synthesis, and their use as HSP-90 inhibitors.