CAS: 38186-84-4; 2-Chloro-5-Fluoro-3-Picoline

相似化合物

34552-15-3 884494-50-2 851484-95-2

上下游产品

CAS号1097264-82-8 (2-chloro-5-flu... | CAS号38186-82-2 5-氨基-2-氯-3-甲基吡啶 | CAS号886365-56-6 2-氨基-3-甲基-5-氟吡啶 | CAS号1256808-59-9 5-氟-3-甲基皮考啉酸

5-氨基-2-氯-3-甲基吡啶置于hexafluorophosphoric Acid体系中,化学反应生成2-氯-3-甲基-5-氟吡啶
参考文献:Non-Basic Histamine H1-Antagonists. I. Synthesis And Biological Evaluation Of Some Substituted 2-(2-Pyridylaminoalkylamino) Pyrimidones And Related Compounds
标题:Non-Basic Histamine H1-Antagonists. I. Synthesis And Biological Evaluation Of Some Substituted 2-(2-Pyridylaminoalkylamino) Pyrimidones And Related Compounds
摘要:
Doi:10.1016/0223-5234(89)90006-8

专利信息

专利号:US-8598361-B2
优先权日:2007-07-31
标题 :Process for preparing 5-fluoro-1H-pyrazolo [3,4-B] pyridin-3-amine and derivatives therof
发明人：JIMENEZ JUAN-MIGUEL; MILLER ANDREW; COLLIER PHILIP; GREEN JEREMY; DROS ALBERT; GAO HUAI; HAMON SYLVAIN
权利人:JIMENEZ JUAN-MIGUEL; MILLER ANDREW; COLLIER PHILIP; GREEN JEREMY; DROS ALBERT; GAO HUAI; HAMON SYLVAIN; VERTEX PHARMA
摘要:The present invention relates to a process for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine in high yield and purity. The present invention also relates to processes for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine derivatives. These processes are useful for preparing biologically active compounds, particularly certain GSK-3 inhibitors, or derivatives thereof.