CAS: 39191-07-6; 1-(3-Chlorophenyl)-N-Methylmethanamine

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CAS号90434-25-6 N-(3-chlorobenz... | CAS号766-80-3 3-氯溴苄 | CAS号74-89-5 氨基甲烷 | CAS号587-04-2 3-氯苯甲醛 | CAS号620-20-2 3-氯氯苄 | CAS号18759-96-1 3-氨基-N-甲基苄胺 | CAS号103264-69-3 N1-(3-氯苄基)-n1-甲...

3-氯苯甲醛置于lithium Aluminium Tetrahydride体系中,用 乙醚 用作溶剂,化学反应 3.0H,反应生成3-氯-N-甲基苄胺
参考文献:Benzylamines: Synthesis And Evaluation Of Antimycobacterial Properties
标题:Benzylamines: Synthesis And Evaluation Of Antimycobacterial Properties
摘要:The Synthesis Of Benzylamines With Various N-Alkyl Chains And Substituents In The Aromatic System As Well As Their Evaluation On Mycobacterium Tuberculosis H 37 Ra Are Described. The Most Active Compounds In This Test,N-Methyl-3-Chlorobenzylamine (19,Mic 10.2 Micrograms/ml),N-Methyl-3,5-Dichlorobenzylamine (93,Mic 10.2 Micrograms/ml),And N-Butyl-3,5-Difluorobenzylamine (103,Mic 6.4 Micrograms/ml),Also Exhibited A Marked Inhibitory Effect On Mycobacterium Marinum And Mycobacterium Lufu Used For The Determination Of Antileprotic Properties. The Combinations Of 93 With Aminosalicylic Acid,Streptomycin,Or Dapsone Exert Marked Supra-Additive Effects On M. Tuberculosis H 37 Ra.
Doi:10.1021/jm00375A005