CAS: 39825-33-7; 2-Propyl (S)-2-Aminopropanoate

相似化合物

62062-65-1 39613-92-8 21691-50-9

上下游产品

isopropyl alcohol rac-Ala-OH L-alanin L-Alanine methyl estercis-3,6-dimethyl-piperazine-2,5-dione(+/-)-cis-3,6-dimethyl-piperazine-2,5-dione (3S,6R)-3,6-dimethylpiperazine-2,5-dione isopropyl alcohol rac-Ala-OH

L-丙氨酸异丙酯盐酸盐 在 三乙胺体系中,用 二氯甲烷作为反应溶剂,反应 0.5H,获得 Isopropyl L-Alanine
参考文献:用于通过 Pn 键形成进行肽标记的荧光 P-羟基磷酯
标题:用于通过 Pn 键形成进行肽标记的荧光 P-羟基磷酯
摘要:本文介绍了一种直接合成新的 P-羟基氧化磷和硫醚基荧光团,这些荧光团表现出大的斯托克斯位移,以及它们通过形成 P-N 键与生物分子的耦合.荧光 P-羟基联萘磷酸-氧化物与生长素释放肽受体 (Ghsr) 拮抗剂偶联,并且通过 Förster 共振能量转移 (Fret) 突出了缀合物的结合.
Doi:10.1002/Chem.202201526

专利信息

专利号:US-10995093-B2
优先权日:2016-04-07
标 题 :Synthesis of 2′-fluoro-6′-methylene-carbocyclic adenosine (FMCA) and 2′-fluoro-6′methylene-carbocyclic guanosine (FMCG)
发明人：CHU CHUNG K; MULAMOOTTTIL VARUGHESE ALEXANDER; MISHRA RAM C; SINGH UMA SHARAN
权利人:UNIV GEORGIA
摘要:The invention provides a new convergent approach for the synthesis of 2′-fluoro-6′-methylene-carbocyclic adenosine (FMCA) and 2′-fluoro-6′-methylene-carbocyclic guanosine (FMCG) from a readily available starting material in eight steps. An efficient and practical methodology for stereospecific preparation of a versatile carbocyclic key intermediate, (1S,3R, 4R)-3-tert-butoxy-4-(tert-butoxymethyl)-2-fluoro-5-methylenecyclopentanol (compound 8 of scheme 1A or a) in only six (6) steps is also provided. Prodrugs of these compounds are also prepared.

专利号:US-2017218006-A1
优先权日:2014-07-31
标题 :Synthesis of Phosphoramidates
发明人：WILHELM THORSTEN; SPITZENSTÄTTER HANS-PETER; SCHÖNE OLGA; RICHTER FRANK; SCHREINER ERWIN
权利人:SANDOZ AG
摘要:A process for the preparation of a compound of formula (I) including all isomers, stereoisomers, enantiomers and diastereomers thereof (I), and salts thereof; the process comprising providing a mixture comprising a compound of formula (II) and a compound of formula (III) subjecting the mixture provided in a) to reaction conditions in the presence of one or more Lewis acids to the mixture provided in a), obtaining a mixture comprising the compound of formula (I).

专利号:WO-2021083438-A1
优先权日:2019-10-30
标 题:Inhibitors of purine nucleoside phosphorylase - synthesis and use thereof for treatment of t-cell acute lymphoblastic leukemia and lymphoma
发明人：SKACEL JAN; JANEBA ZLATKO; MERTLIKOVA KAISEROVA HELENA
权利人:USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I
摘要:The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

专利号:EP-3174892-A1
优先权日:2014-07-31
标 题:Synthesis of phosphoramidates

专利号:US-2014309413-A1
优先权日:2013-03-11
标题 :Methods of stereoselective synthesis of substituted nucleoside analogs
发明人：ROSE PETER JAMISON; JUNG YOUNG CHUN; BLIGH CAVAN MCKEON; IBRAHIM SHEREEN; ANZALONE LUIGI; MILLER JR DAVID B; VAN ALSTEN JOHN GREGG; CURRAN TIMOTHY THOMAS
权利人:VERTEX PHARMA
摘要:The present invention relates to the novel diastereoselective syntheses for generating phosphorothioate compounds. Examples include nucleoside phosphorothioate analogs that are useful in treating diseases and/or conditions such as viral infections.

专利号:US-2011245484-A1
优先权日:2010-03-31
标 题 :Stereoselective synthesis of phosphorus containing actives