CAS: 707-60-8; 4-Bromo-N,N-Dimethylbenzenesulfonamide

上下游产品

bromobenzene dimethyl amine 4-bromobenzenesulfonyl chloride para-bromobenzenethiol 4-(2-Hydroxymethyl-phenylsulfanyl)-N,N-dimethyl-benzenesulfonamide N,N-Dimethyl-4-brombenzolsulfamid 4-(2-Chloromethyl-phenylsulfanyl)-N,N-dimethyl-benzenesulfonamide 4-(2-Cyanomethyl-phenylsulfanyl)-N,N-dimethyl-benzenesulfonamide

4-氨基-N,N-二甲基苯磺酰胺置于三氯溴甲烷,Sodium Nitrite,溶剂黄146体系中,用 二氯甲烷,水 作为反应溶剂,化学反应 1.08H,以98%的收率获得产物4-溴-N,N-二甲基苯磺酰胺
参考文献:一锅,无金属地将苯胺转化为芳基溴化物和碘化物
标题:一锅,无金属地将苯胺转化为芳基溴化物和碘化物
摘要:描述了通过从溴代三氯甲烷和二碘代甲烷中提取卤素从苯胺无金属合成芳基溴化物和碘化物.该一锅法反应以中等至优异的收率从相应的苯胺提供了卤代芳基卤化物,而没有分离出重氮盐.该转化反应时间短,后处理简单,对湿气和空气不敏感,并且避免了过多的卤化.dft计算支持s Rn 1机制.此方法代表了经典sandmeyer反应的一种方便替代方法.
DOI:10.1021/acs.Orglett.7B00771

专利信息

专利号:EP-1546186-A4
优先权日:2002-08-26
标题 :PROCESS FOR SYNTHESIS OF PEPTIDES

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.

专利号:CN-116947712-A
优先权日:2023-07-25
标题:Synthesis method of sulfonamide organic compound

专利号:CN-119822988-A
优先权日:2025-02-14
标题 :A photochemical synthesis method of formanilide compounds