CAS: 1643-20-5; N,N-Dimethyldodecan-1-Amine Oxide

相似化合物

3332-27-2 17206-00-7 124-28-7

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CAS号112-18-5 十二烷基二甲基叔胺 | CAS号112-18-5 十二烷基二甲基叔胺

十二烷基二甲基叔胺置于乙二胺四乙酸,2,2,2-三氟苯乙酮,Sodium Carbonate,Potassium Carbonate,Potassium Hydrogencarbonate体系中,用 水 用作溶剂,化学反应 5.0H,以97%的收率获得月桂基二甲基氧化胺
参考文献:电化学生成过氧二碳酸酯的胺氧化
标题:电化学生成过氧二碳酸酯的胺氧化
摘要:叔胺的n氧化是通过使用电化学产生的过氧化二碳酸盐溶液作为可持续氧化剂来实现的.发现 Edta 和 2,2,2-三氟苯乙酮作为介质的存在对于转化水不溶性底物至关重要.各种叔胺以高达 98% 的收率转化为其相应的n-氧化物.范围包括经济上重要的表面活性剂和潜在的平台氧化剂.
Doi:10.1055/a-1860-3405

专利信息

专利号:US-2012190064-A1
优先权日:2004-10-01
标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
发明人：KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

专利号:US-6451543-B1
优先权日:1998-08-31
标题:Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
发明人：KOCHENDOERFER GERD G; HUNTER CHRISTIE L; KENT STEPHEN B H; BOTTI PAOLO
权利人:GRYPHON SCIENCES
摘要:The present invention relates to methods and compositions for lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides that are incorporated in a lipid matrix. The invention is exemplified in production of a prefolded membrane polypeptide embedded within a lipid matrix via stepwise chemoselective chemical ligation of unprotected peptide segments, where at least one peptide segment is embedded in a lipid matrix. Any chemoselective reaction chemistry amenable for ligation of unprotected peptide segments can be employed. Suitable lipid matrices include liposomes, micelles, cell membrane patches and optically isotropic cubic lipidic phase matrices. Prefolded synthetic and semi-synthetic membrane polypeptides synthesized according to the methods and compositions of the invention also permit site-specific incorporation of one or more detectable moieties, such as a chromophore, which can be conveniently introduced during synthesis. The methods and compositions of the invention have multiple uses. For example, they can be used to assay ligand binding to membrane polypeptides and domains comprising a receptor, and thus are extremely useful for structure/function studies, drug screening/selection/design, and diagnostics and the like, including high-throughput applications. The methods and compositions of the invention are particularly suited for FRET analyses of previously inaccessible membrane polypeptides.

专利号:US-2006211083-A1
优先权日:2005-01-21
标题:Products and processes for in vitro synthesis of biomolecules
发明人：KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
权利人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
摘要:Provided herein are products and processes for efficiently synthesizing biomolecules in vitro using cell-free extracts derived from mammalian cells and insect cells. In an embodiment, provided is a process for preparing a cell-free extract from insect cells and mammalian cells that efficiently synthesizes post-translationally modified target proteins (e.g., glycosylated target proteins). In some embodiments, a ribonucleic acid is synthesized in vitro that comprises a cap, a 5′ untranslated region comprising an 18S rRNA binding ribonucleotide sequence, and a target ribonucleotide sequence. It has been determined that such ribonucleic acids result in efficient in vitro synthesis of a target protein using cell-free extracts derived from non-rabbit mammalian cells and insect cells.

专利号:US-12037623-B2
优先权日:2018-07-09
标 题 :Enzymatic synthesis of 4′-ethynyl nucleoside analogs
发明人：HUFFMAN MARK A; FRYSZKOWSKA ANNA; KOLEV JOSHUA N; DEVINE PAUL N; CAMPOS KEVIN R; TRUPPO MATTHEW; NAWRAT CHRISTOPHER C
权利人:MERCK SHARP & DOHME; MERCK SHARP & DOHME LLC
摘要:The present invention relates to an enzymatic synthesis of 4′-ethynyl-2′-deoxy nucleosides and analogs thereof, for example EFdA, that eliminates the use of protecting groups on the intermediates, improves the stereoselectivity of glycosylation and reduces the number of process steps needed to make said compounds. It also relates to the novel intermediates employed in the process.

专利号:US-2024309142-A1
优先权日:2023-03-17
标题 :Capped block copolymers, their synthesis, manufacture, and methods of use
发明人：MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON
权利人:ECOLAB USA INC
摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.

专利号:US-2024417358-A1
优先权日:2021-10-04
标题:Continuous Flow Reactor and Process for Synthesis of Substituted Benzoic Acid
发明人：JOSHI SUNIL SHANKAR; MALI NILESH ATMARAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a non-hazardous, improved continuous oxidation process for the preparation of substituted benzoic acid of formula (I) by using continuous process reactor system with improved process controls. (I) wherein: R 1 is H, F, Cl, Br, I, NO 2 , amine, or C 1 -C 5 alkyl; R 2 is H, F, Cl, Br, I, NO 2 , amine, or C 1 -C 5 alkyl; and R 3 is H, F, Cl, Br, I, NO 2 , amine, C 1 -C 5 alkyl;