CAS: 22427-39-0; Ginsenoside Rg1

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CAS号52286-59-6 人参皂苷Re | CAS号163403-91-6 6-O-[6-O-acetyl... | CAS号53963-43-2 人参皂苷 F1 | CAS号492-61-5 β-D-葡萄糖 | CAS号80952-71-2 (20R)-人参皂苷Rh1

6-O-[6-O-Acetyl-β-D-Glucopyranosyl]-20-O-(β-D-Glucopyranosyl)-20(S)-Protopanaxatriol置于ammonium Hydroxide体系中,化学反应 16.0H,以1.8 Mg的收率获得人参皂苷 Rg1
参考文献:Dammarane-Type Triterpene Saponins From Panax Japonicus
标题:Dammarane-Type Triterpene Saponins From Panax Japonicus
摘要:Six New Dammarane-Type Saponins (1-6),Together With 11 Known Saponins (7-17),Were Isolated From Ye-Sanchi,The Underground Part Of Panax Japonicus Collected In The South Of Yunnan Province,China. Their Structures Were Elucidated By Chemical And Spectroscopic Means.
Doi:10.1021/np010354J

专利信息

专利号:US-5801192-A
优先权日:1995-08-25
标题 :Use of vitamin C or derivatives or analogues thereof promoting skin elastin synthesis
发明人：DUMAS MARC; BONTE FREDERIC; MEYBECK ALAIN; CHAUDAGNE CATHERINE
权利人:LVMH RECH
摘要:The invention relates to the use of ascorbic acid, notably L-ascorbic acid or vitamin C, or of its erythorbic acid isomer, or of their salts or esters, for promoting the synthesis of elastin in the dermis in the view of improving in particular skin elasticity. n The invention enables manufacturing cosmetic or pharmaceutical compositions, notably dermatological compositions, for improving skin elasticity, for example in the context of a product which improves skin tone or skin firmness. n The invention also enables increasing the elastin content of artificial dermes.

专利号:US-7811612-B2
优先权日:2005-01-20
标 题 :Herbal mixture extract of notoginseng radix, rehmanniae radix preparata and acanthopanacis cortex and composition comprising the same for prevention and treatment of arthritis
发明人：KIM JUNG-KEUN; KIM SE-WON; KIM HYUNG-GUN; KO SEON-YLE; BAEK DONG-HEON; CHANG SUNHWA
权利人:OSCOTEC INC
摘要:The present invention relates to an extract of an herbal mixture of Notoginseng radix, Rehmanniae radix preparata and Acanthopanacis cortex , and a method for treating arthritis using the extract as an effective ingredient. The extract of the herbal mixture of the present invention can effectively inhibits the release of inflammatory substances and the synthesis of cartilage destroying substance as well as the progress of arthritis.

专利号:US-9783838-B2
优先权日:2011-11-07
标 题 :PmST3 enzyme for chemoenzymatic synthesis of alpha-2-3-sialosides
发明人：CHEN XI; THON VIREAK; YU HAI
权利人:UNIV CALIFORNIA
摘要:The present invention provides novel methods for preparing glycosylated molecules such as oligosaccharides, glycolipids, and glycoproteins/peptides. Novel sialyltransferases are also disclosed. The method includes forming a reaction mixture containing an acceptor molecule, a donor substrate having a sugar moiety and a nucleotide, and a sialyltransferase selected from PmST3 (SEQ ID NO:7) and certain variants thereof. The reaction mixture is formed under conditions sufficient to transfer the sugar moiety from the donor substrate to the acceptor molecule, thereby forming the glycosylated molecule. In some embodiments, the acceptor molecule is selected from a natural product, an oligosaccharide, a glycoprotein, and a glycolipid. In some embodiments, the donor substrate is formed via conversion of a suitable hexosamine derivative to a cytidine 5′-monophosphate(CMP)-sialic acid in a one-pot reaction mixture containing asialic acid aldolase and a CMP-sialic acid synthetase.

专利号:US-5747538-A
优先权日:1994-03-18
标 题 :Use of ginsenoside R0 or a plant extract containing same to promote collagen synthesis
发明人：MEYBECK ALAIN; BONTE FREDERIC; DUMAS MARC; CHAUDAGNE CATHERINE
权利人:LVMH RECH
摘要:PCT No. PCT/FR95/00326 Sec. 371 Date Sep. 18, 1996 Sec. 102(e) Date Sep. 18, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25524 PCT Pub. Date Sep. 28, 1995The use of ginsenoside R0 or a plant extract containing same to prepare a cosmetic or pharmaceutical composition, particularly a skin care composition, for promoting collagen synthesis, particularly collagen I and/or collagen III synthesis. Said cosmetic or pharmaceutical composition is administered to a mammal, particularly a human being, in order to promote collagen synthesis. A method for promoting collagen synthesis in fibroblast growth media is also disclosed.

专利号:WO-2023249340-A1
优先权日:2022-06-20
标 题 :High-purity ginseng exosome composition and use thereof in functional cosmetics
发明人：CHO YONG WOO; CHOI JI SUK; CHOI YOUNG CHAN; LEE HYE RI
权利人:EXOSTEMTECH CO LTD; IUCF HYU ERICA CAMPUS
摘要:The present invention relates to a functional cosmetic composition comprising plant exosomes derived from ginseng as its active ingredient, and functional cosmetics containing same. Ginseng exosomes have a bilipid layer structure and are rich in ginsenosides Rb1 and Rg1, which influence skin improvement and whitening. It has been proven that these powerful functional materials, ginsenosides Rb1 and Rg1, are absorbed in large quantities through ginseng exosomes into skin cells, enhance the synthesis of collagen and hyaluronic acid in skin cells, and have the efficacy of inhibiting melanin synthesis. Therefore, the ginseng exosomes rich in ginsenosides Rb1 and Rg1, as presented in the present invention, can be beneficially used in functional cosmetic compositions for skin aging prevention, skin whitening, wrinkle reduction, and skin cell regeneration.

专利号:US-2007060499-A1
优先权日:2005-09-15
标 题 :Chloroquine combination drugs and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.