CAS: 554-62-1; (2S,3S,4R)-2-Aminooctadecane-1,3,4-Triol

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上下游产品

CAS号175696-50-1 N-tert-Butyloxy... | CAS号1094213-81-6 (2S,3S,4R)-1-(t... | CAS号123-78-4 D-鞘氨醇 | CAS号34354-88-6 N-硬脂酰植物鞘氨醇 | CAS号103348-49-8 (2S,3R,4E)-2-叠氮... | CAS号116467-63-1 (4E,2S,3R)-1,3-...

(S)-Tert-Butyl 4-[(1S,2R)-1,2-Dihydroxyhexadecyl]-2,2-Dimethyloxazolidine-3-Carboxylate置于三氟乙酸体系中,用 水 作为反应溶剂,以68%的收率获得产物糖脂
参考文献:在向l-丝氨酸衍生的旋光醛中添加亲核试剂的立体控制,导致(2 S,3 S,4 R)-植物鞘氨醇的短步合成
标题:在向l-丝氨酸衍生的旋光醛中添加亲核试剂的立体控制,导致(2 S,3 S,4 R)-植物鞘氨醇的短步合成
摘要:非对映选择性地将二噻吩胺加到衍生自l-丝氨酸的手性醛中,然后将二噻吩基部分水解,再加入十二烷基乙酰胺,得到非对映体纯的氨基三醇衍生物,经氢化和脱保护后得到(2 S,3 S,4 R)-植物鞘氨醇,对映体纯形式,总收率好.
DOI:10.1016/s0040-4039(97)01340-3

专利信息

专利号:US-2024024489-A1
优先权日:2020-11-20
标 题:Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
发明人：MULARD LAURENCE; DHARA DEBASHIS; PFISTER HELENE; PAOLETTI JULIE; PHALIPON ARMELLE; GUERREIRO-INVERNO CATHERINE
权利人:PASTEUR INSTITUT
摘要:The present invention provides zwitterionic oligosaccharides, in particular fragments of the surface polysaccharides from Shigella sonnei and Shigella sonnei conjugates comprising them. The present invention also provides protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof, the disaccharide repeating unit of Shigella sonnei being: (I)

专利号:WO-2024165611-A1
优先权日:2023-02-07
标题:Production of a disaccharide and/or milk oligosaccharide by a cell with reduced synthesis of udp-glcnac
发明人：BEAUPREZ JOERI; DECOENE THOMAS; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The invention provides a cell for production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide wherein synthesis of UDP-N-acetylglucosamine in said cell is rendered less functional. The invention further provides use of said cell in a cultivation or incubation. The invention also describes methods for the production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide using said cell as well as the purification of said disaccharide and/or oligosaccharide like a milk oligosaccharide.

专利号:US-8647848-B2
优先权日:2008-06-13
标题:Enzymatic synthesis of sphingolipids
发明人：HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS
权利人:HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS; EVONIK GOLDSCHMIDT GMBH
摘要:The invention relates to the enzymatic synthesis of sphingolipids and compositions that contain sphingolipids from lysosphingolipids and carbonic esters, and to cosmetic, dermatological or pharmaceutical formulations containing said sphingolipids or compositions.

专利号:WO-2024165524-A1
优先权日:2023-02-06
标 题:Production of a saccharide by a cell with reduced synthesis of lactobionic acid
发明人：BEAUPREZ JOERI; DECOENE THOMAS; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The invention provides a cell for production of a saccharide wherein synthesis of lactobionic acid in said cell is rendered less functional or is knocked out. The invention further provides use of said cell in a cultivation or incubation. The invention also describes methods for the production of a saccharide using said cell as well as the purification of said saccharide.

专利号:US-5262312-A
优先权日:1990-04-25
标 题:Process for the glycosidase-catalyzed synthesis of glyco conjugates
发明人：HOLLA WOLFGANG; SCHUDOK MANFRED
权利人:HOECHST AG
摘要:It has been possible to show for a first time with the process according to the invention that the synthesis of glyco conjugates is possible by direct linkage of sugars with serine, serine derivatives and serine peptides with the aid of glucosidases.

专利号:US-9802974-B2
优先权日:2012-07-24
标 题 :Synthesis of diverse glycosylphosphatidylinositol glycans from Toxoplasma gondii and their application as vaccines and diagnostics
发明人：AZZOUZ NAHID; GÖTZE SEBASTIAN; SEEBERGER PETER H; SILVA DANIEL VARON; TSAI YU-HSUAN
权利人:MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V
摘要:The present invention relates to the synthesis of GPI-related surface antigens of the parasite Toxoplasma gondii ( T. gondii ) and the resulting products obtained. These synthetic compounds are suitable for diagnosis of toxoplasmosis, as well as vaccine against toxoplasmosis, a diseases caused by infection with T. gondii.