CAS: 7459-46-3; Triethyl Ethane-1,1,2-Tricarboxylate

相似化合物

5472-38-8 632-56-4 133-13-1

上下游产品

diethyl 2-cyanosuccinate ethanol tetrachloromethane Oxalyl bromideH-pyrazole-3-carboxylic acid5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxylic acid 2-piperonylsuccinic acid 2-Ethoxycarbonyl-2-(4-nitro-benzyl)-succinic acid diethyl ester 2-(4-Chloro-benzyl)-2-ethoxycarbonyl-succinic acid diethyl ester

溴乙酸乙酯置于sodium Hydride体系中,用 四氢呋喃 作为反应溶剂,化学反应 5.5H,以64%的收率获得产物1,1,2-乙烷三羧酸三乙酯
参考文献: Dutpase Inhibitors[fr] Inhibiteurs De Dutpase
标题: Dutpase Inhibitors[fr] Inhibiteurs De Dutpase
摘要:脱氧尿嘧啶衍生物的公式(I),其中r1是h或不同的取代基;d是-Nhco-,-Conh-,-0-,-C(=o)-,-Ch=ch,-Cξc-,-Nr5-;r4是氢或不同的取代基;r5是h,C1-C4烷基,C1-C4烷酰基;e是si或c;r6,R7和r8独立地选自c1-C8烷基,C2-C8烯基,C2-C8炔基或稳定的单环,双环或三环环系;g是-O-,-S-,-Chr10-,-C(=o)-;j是-Ch2-,或者当g是chr10时,也可以是-O-或-Nh-;r10是h,F,-Ch3,-Ch2Nh2,-Ch2Oh;-Oh R11是h,F,-Ch3,-Ch2 Nh2,-Ch2Oh,Ch(Oh)Ch3,Ch(Nh3)Ch3;或者r10和r11共同定义一个烯丙基键,或者共同形成一个-Ch2-基团,从而定义一个顺式或反式环丙基基团;在预防或治疗疟疾等原虫性疾病方面具有用途.

专利信息

专利号:US-2011124634-A1
优先权日:2008-05-13
标 题:Bioactive compounds for treatment of cancer and neurodegenerative diseases
发明人：SUN CONNIE L; LI XIAOYUAN
权利人:PONIARD PHARMACEUTICALS INC
摘要:The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.

专利号:US-4215062-A
优先权日:1978-05-22
标 题 :Anthracycline synthesis
发明人：MITSCHER LESTER A
权利人:KANSAS UNIV ENDOWMENT ASS THE
摘要:A process for synthesizing doxorubicin and related compounds from aloe-emodin is disclosed. Intermediates useful in the preparation of doxorubicin and related compounds are also disclosed.

专利号:CN-107226798-A
优先权日:2017-06-27
标题:A New Process for the Synthesis of 3-Tetrahydrofuran Methanol by Prins Reaction

专利号:CN-107141273-A
优先权日:2017-06-27
标题 :A new process for the synthesis of tetrahydrofuran-3-methanol by one-pot method

专利号:CN-1405141-A
优先权日:2002-11-04
标 题:Synthesis method and application of a class of fluorine-containing polycarboxylic acid compounds