CAS: 82611-88-9; N-Ethyl-N-(3-Sulfopropyl)-M-Anisidine Sodium Salt

专利信息

专利号:US-12378221-B2
优先权日:2022-07-05
标 题:Salts of obicetrapib and processes for their manufacture and intermediates thereof
发明人：CUI SHENG; RÖTHELI ANDREAS RENÉ; BORTHS CHRISTOPHER J; KISHIDA MUNEKI; SMOLENSKAYA VALERIYA NIKOLAYEVNA
权利人:NEWAMSTERDAM PHARMA B V
摘要:Provided herein is a method for the manufacture of a compound of obicetrapib and salts thereof, such as calcium salts thereof. Also provided herein is amorphous obicetrapib hemicalcium. New intermediates for use in the synthesis of obicetrapib, and salts thereof are also provided, including obicetrapib HCl and a mesylate salt for the use in the synthesis of obicetrapib and amorphous obicetrapib hemicalcium.

专利号:US-2024132927-A1
优先权日:2020-12-02
标 题 :Modular glycan production with immobilized bionanocatalysts
发明人：CORGIE STEPHANE CEDRIC; HOEPKER ALEXANDER CHRIS
权利人:ZYMTRONIX CATALYTIC SYSTEMS INC
摘要:The invention provides modular cell-free de-novo synthesis of glycans with immobilized bionanocatalysts. The invention provides materials, and in particular, magnetic materials, for producing glycans of defined length and sequences using one or more enzymes that are immobilized within bionanocatalysts (BNCs) which in turn are embedded within scaffolds to control the synthesis in batch or continuous processes manufacturing. In some embodiments, the scaffolds are high magnetism and high porosity composite blends of thermoplastics or thermosets comprising magnetic particles that form powders. In some embodiments, Selective Laser Sintering (SLS) is used to design and produce objects via 3D printing by sintering composite magnetic powders. The modular flow cells may be mixed and matched for a highly customizable and highly efficient cell-free manufacturing process. In some embodiments the elementary and system modules provided by the invention are employed. In preferred embodiments, human milk oligosaccharides (HMOs) are produced.

专利号:US-2015366923-A1
优先权日:2013-03-14
标题 :Allamanda cathartica extracts and methods of use
发明人：MEI BING C; LYGA JOHN W
权利人:AVON PROD INC
摘要:Methods of using extracts of Allamanda cathartica to impart benefits to skin and/or improve skin conditions resulting from aging or damaged skin are provided, said methods comprising applying the extacts of Allamanda cathartica in pharmaceutically and cosmetically acceptable formulations to the skin surface, which results in activation of collagen synthesis and leads to skin lightening and anti-wrinkle effects.

专利号:US-2013224318-A1
优先权日:2012-02-29
标 题 :Use of CPT-1 Modulators and Compositions Thereof
发明人：HWANG CHENG S; YIM SUNGHAN; SANTHANAM UMA; LYGA JOHN W
权利人:AVON PROD INC; AVON PROD INC
摘要:The present invention describes methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising Carnitine Palmitoyl Transferase-1 (CPT-1) modulators, optionally with other anti-lipid agents; and also describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis.