CAS: 25033-19-6; 1-Cyclopropylnaphthalene

相似化合物

1533519-92-4 127971-24-8 1824263-97-9

上下游产品

CAS号90-11-9 1-溴代萘 | CAS号23719-80-4 环丙基溴化镁 | CAS号411235-57-9 环丙基硼酸 | CAS号826-74-4 1-乙烯基萘 | CAS号74-95-3 二溴甲烷 | CAS号1065010-87-8 环丙基三氟硼酸钾 | CAS号27650-86-8 1-(3-bromopropy... | CAS号878671-94-4 4-环丙基-1-萘胺

3-萘-3-氧丙酸甲酯置于盐酸,Sodium Hydroxide体系中,用 水 用作溶剂,化学反应 11.0H,以12.7 Kg的收率获得1-环丙基萘
参考文献:一种1-环丙基萘的制备方法
标题:一种1-环丙基萘的制备方法
摘要:本发明公开了一种1‑环丙基萘的制备方法,包括以下步骤:化合物1在酸性条件下进行关环反应,得到3‑(1‑萘基)二氢呋喃‑2(3H)‑酮;3‑(1‑萘基)二氢呋喃‑2(3H)‑酮在碱性条件下形成环丙基,得到1‑环丙基萘.本发明提供的制备方法解决了1‑环丙基萘生产中出现的反应条件苛刻,反应产生污染,反应危险程度高及不利于放大生产等一系列问题.

专利信息

专利号:US-9296709-B2
优先权日:2012-07-03
标 题 :Manufacture of 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid
发明人：GUNIC ESMIR; GALVIN GABRIEL
权利人:ARDEA BIOSCIENCES INC
摘要:Described herein are certain processes for the synthesis of compounds of Formula (I):

专利号:US-2024300982-A1
优先权日:2023-03-03
标题 :Reactive secondary boranes and methods for synthesis thereof
发明人：Martin Caleb; AKRAM MANJUR
权利人:UNIV BAYLOR
摘要:A secondary borane featuring two ortho-carborane substituents [HBoCb2, oCb=ortho-carborane] is useful as a powerful hydroboration reagent. The Lewis superacid, bis(1-methyl-ortho-carboranyl)borane, is rapidly accessed in two steps. It is a very effective hydroboration reagent capable of the hydroboration of alkenes, alkynes, cyclopropanes, and allenes. The large steric profile prevents double hydroboration of alkynes and promotes regioselectivity in allenes. The compound is a Lewis superacidic secondary borane and effective neutral hydroboration reagent.

专利号:US-6228955-B1
优先权日:1996-04-19
标题:Asymmetric epoxides, their synthesis and use
发明人：ROBERTS STANLEY MICHAEL; ADGER BRIAN MICHAEL
权利人:CHIROTECH TECHNOLOGY LTD
摘要:A process for preparing an optically-enriched chiral epoxide of formula I n wherein R 1 , R 2 and R 3 are each independently selected from H, R, R—CO— and R—O—CO—, each R independently being substantially a hydrocarbon group of up to 20 carbon atoms, and X is an alkyl or cycloalkyl group of up to 10 carbon atoms, provided that —CO—X is not enolisable, which comprises the asymmetric epoxidation of a corresponding prochiral alkene of formula II n n n R 1 R 2 Câ•?CR 3 —CO—X  (II) n n n by reaction with an oxidant in the presence of a chiral catalyst. Many optically-enriched epoxides (I) are novel.

专利号:WO-2006079916-A1
优先权日:2005-01-26
标 题 :Thieno [2,3-d] pyrimidine compounds as inhibitors of adp-mediated platelets aggregation
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
权利人:PHARMACIA & UPJOHN CO LLC; ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:EP-2402011-A1
优先权日:2004-08-25
标题:Intermediates in the synthesis of S-triazolyl alpha-mercaptoacetanildes as inhibitors of HIV reverse transcriptase

专利号:CN-118390073-A
优先权日:2024-05-23
标题:A method for organic electrochemical synthesis of cyclopropane compounds