CAS: 28721-07-5; 10-Oxo-10,11-Dihydro-5H-Dibenzo[b,F]Azepine-5-Carboxamide

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CAS号29331-92-8 10-羟基-10,11-二氢-... | CAS号4698-11-7 10-甲氧基亚氨基芪 | CAS号917-61-3 氰酸钠 | CAS号28721-09-7 10-甲氧卡马西平 | CAS号3564-73-6 双氢卡马西平 | CAS号100-52-7 苯甲醛 | CAS号32315-10-9 三光气 | CAS号1189-71-5 氯磺酰异氰酸酯 | CAS号21737-58-6 5H-二苯并[b,f]氮杂环庚... | CAS号75-07-0 乙醛 | CAS号19579-83-0 二苯并氮杂卓-10,11-二酮 | CAS号104746-03-4 R-10-单羟基二氢卡马西平 | CAS号104746-04-5 艾司利卡西平 | CAS号113952-21-9 (11-carbamoyl-5... | CAS号21737-58-6 5H-二苯并[b,f]氮杂环庚... | CAS号29331-92-8 10-羟基-10,11-二氢-...

10-Methoxy-5H-Dibenz[b,F]Azepine-5-Carboxylic Acid Methyl Ester置于sodium Hydroxide,硫酸,溶剂黄146体系中,用 Various Solvent(S) 用作溶剂,化学反应 28.0H,反应生成奥卡西平
参考文献:使用friedel-Crafts环化策略的新合成奥卡西平
标题:使用friedel-Crafts环化策略的新合成奥卡西平
摘要:已经开发出一种新颖,简单,直接的大规模合成奥卡西平的方法,奥卡西平是治疗癫痫的药物,特立普妥®的活性成分.从容易获得的1,3-二氢-1-苯基-2 H-吲哚-2-酮开始,Friedel-Crafts环化策略提供了通往目标分子三环骨架的直接途径.该策略成功的关键是选择合适的氮保护基.
Doi:10.1016/j.Tetlet.2004.05.014

专利信息

专利号:US-10022446-B2
优先权日:2014-08-22
标题 :PH responsive hybrid hydrogel and method of synthesis thereof
发明人：KIZILEL SEDA; CEVIK OZLEM
权利人:KOC UENIVERSITESI
摘要:A pH-responsive hybrid hydrogel, namely poly(Methacrylic acid-grafted-Ethylene Glycol) P(MAA-g-EG) cross-linked with Styrene-Butadiene-Styrene (SBS) polymer and photopolymerized by visible light. The resulting polymer turned out to have better integrities, high swelling ratios, pH-responsive and biocompatible character. Also the visible-light-induced synthesis of these pH-responsive composite wherein eosin Y is used as photoinitiator and triethanolamine is used as a co-initiator is also disclosed in the invention.

专利号:US-7576211-B2
优先权日:2004-09-30
标题 :Synthesis of thienopyridinone compounds and related intermediates
发明人：DHANOA DALE S; BECKER OREN; NOIMAN SILVIA; CHEN DONGLI; MARANTZ YAEL; SHACHAM SHARON; HEIFETZ ALEXANDER; INBAL BOAZ; BAR-HAIM SHAY; MOHANTY PRADYUMNA; LOBERA MERCEDES; WU LAURENCE
权利人:EPIX DELAWARE INC
摘要:The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.

专利号:WO-2016028237-A1
优先权日:2014-08-22
标题 :A novel ph responsive hydrogel and method of synthesis
发明人：KIZILEL SEDA; CEVIK OZLEM
权利人:KOÇ ÃœNIVERSITESI
摘要:A pH-responsive hydrogel, namely poly(Methacrylic acid-grafted-Ethylene Glycol) P(MAA-g-EG), that is synthesized via photopolymerization that is initiated by visible light with enhanced swelling properties as compared to P(MAA-g-EG) hydrogel that is synthesized through UV-light initiated photopolymerization technique. Also the method of synthesis of the said hydrogel and the use of the hydrogel in pharmacy for drug delivery applications.

专利号:US-2022233673-A1
优先权日:2019-06-04
标 题:METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF
发明人：BILLET ANNE; SCHMIDT FRÉDÉRIC; JOHANNES LUDGER; SERVENT DENIS; MOURIER GILLES; TARTOUR ÉRIC; KAY MICHAEL; FULCHER JAMES M
权利人:INST CURIE; CENTRE NAT RECH SCIENT; INST NAT SANTE RECH MED; COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES CEA; APHP ASSIST PUBLIQUE HOPITAUX DE PARIS; UNIV PARIS; UNIV OF UTAH RESEARCH FOUDATION; UNIV UTAH RES FOUND
摘要:A method of producing a monomer of a Shiga toxin B-subunit (STxB) protein or of a variant thereof by peptide chemical synthesis, as well as to a method of producing a pentamer of the STxB protein or of the variant thereof. The methods are particularly advantageous as they overcome major issues typically observed in peptide chemical synthesis, including solubility and purity issues.

专利号:US-2008214827-A1
优先权日:2004-02-03
标 题:Synthesis of Cyanoimino-Benzoimidazoles
发明人：GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
权利人:EURO CELTIQUE SA
摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

专利号:US-2011040105-A1
优先权日:2008-04-16
标题 :Processes useful for the synthesis of (r)-1--2-methyl-pyrrolidine
发明人：HUBER CHRISTIAN H; KHULMAN YOUNG MI; TANDEL SAGUN K; JOHANNSEN STEPHEN R; WANG TINGMIN; ANGELL PAUL
权利人:ARENA PHARM INC
摘要:Processes useful for making a pharmaceutically useful compound according to Formula (I), forms of such a compound, and intermediates useful in such processes are described.