CAS: 29274-28-0; 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine

相似化合物

2105905-46-0 1240725-66-9 117007-51-9

上下游产品

1H-吡唑并[3,4-B]吡啶 1H-Pyrazolo[3,4-B]Pyridine 271-73-8

2-氯-3-吡啶甲醛置于对甲苯磺酸,甲基磺酰氯,肼体系中,用 乙酸乙酯,N,N-二甲基甲酰胺 用作溶剂,化学反应 14.17H,反应生成4-氯-7-氮杂吲唑,4-氯吡唑并[3,4-B]吡啶
参考文献:Multikinase Inhibitor
标题:Multikinase Inhibitor

专利信息

专利号:US-9951062-B2
优先权日:2012-12-14
标 题 :Substituted 1 H-pyrrolo [2, 3-b] pyridine and 1 H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
发明人：VANKAYALAPATI HARIPRASAD; YERRAMREDDY VENKATAKRISHNAREDDY; GANIPISETTY VENU BABU; TALLURI SURESHKUMAR; APPALANENI RAJENDRA P
权利人:ARRIEN PHARMACEUTICALS LLC
摘要:Compounds according to Formulas I, IA or IB: n nto pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and/or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.