CAS: 35044-57-6; Ethyl 2,6,6-Trimethyl-2,4-Cyclohexadiene-1-Carboxylate

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合成工艺路线路线简述

    3-氧代-2-(2-亚丙基)丁酸乙酯置于正丁基锂体系中,用 乙醚,水 作为反应溶剂,化学反应生成 6,6-二甲基-2-亚甲基-3-环己烯-1-羧酸乙酯
    参考文献:Ring-Labeled Retinoids And Intermediates,And Methods For Their
    标题:Ring-Labeled Retinoids And Intermediates,And Methods For Their
    摘要:提供了合成二氘和/或二氚环标记的视黄醇类化合物和中间体的方法,以及它们在发现视黄醇x受体配体中的应用.此外,还提供了二氘和/或二氚环标记的视黄醇类化合物和新型中间体,以及用于配体结合和质谱研究的方法.

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    专利信息


    专利号:US-5514821-A
    优先权日:1994-05-27
    标 题 :Ring-labeled retinoids and intermediates, and methods for their synthesis and use
    发明人:BENNANI YOUSSEF L; BOEHM MARCUS F
    权利人:LIGAND PHARM INC
    摘要:Methods for the synthesis of dideuterium and/or ditritium ring-labeled retinoids and intermediates, and their use in the discovery of Retinoid X Receptor ligands are provided. In addition, dideuterium and/or ditritium ring-labeled retinoids and novel intermediates, as well as methods for their use in ligand binding and mass spectral studies are also provided.

    专利号:US-2025034074-A1
    优先权日:2021-11-25
    标题:Process for preparing a cyclic diene
    发明人:JACOBY DENIS; CHAPPUIS SIMONE; KELLER FABRICE
    权利人:FIRMENICH & CIE
    摘要:The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) comprising the reaction of a compound of the formula (II) with a base having a boiling point superior to the boiling point of the compound of formula (I). Moreover, the compound of formula (I) and the compound of formula (II) are also part of the invention.

    专利号:US-4028278-A
    优先权日:1971-08-17
    标 题 :Cycloaliphatic unsaturated ketones as fragrance modifying agents
    发明人:BUCHI GEORGE H; WUEST HANS
    权利人:FIRMENICH & CIE
    摘要:New cycloaliphatic unsaturated ketones and their use as perfuming and odor-modifying agents in the manufacture of perfumes and perfumed products, and as flavoring and taste-modifying agents in the preparation of foodstuffs in general and imitation flavors for foodstuffs, beverages, animal feeds, pharmaceutical preparations and tobacco products. n Methods for preparing the said new compounds and certain of the starting materials used for their synthesis.
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    合成参考文献


    摘要:Bergsträßer, U.; Hartung, J., Science of Synthesis, (2009) 38, 78.
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