CAS: 3749-36-8; 3,4-Dihydro-2H-Pyran-2-Methanol

相似化合物

21193-75-9 68691-34-9 67666-30-2

上下游产品

CAS号100-73-2 2-甲酰基-3,4-二氢吡喃 | CAS号16698-52-5 3,4-二氢吡喃2-羧酸钠 | CAS号3540-36-1 3,4-dihydro-2H-... | CAS号83568-11-0 3,4-二氢-2H-吡喃-2-羧酸乙酯 | CAS号74-88-4 碘甲烷 | CAS号20583-51-1 6,8-dioxabicycl... | CAS号20583-51-1 6,8-dioxabicycl... | CAS号22347-71-3 2H-Pyran-2-meth... | CAS号280-16-0 6,8-Dioxabicycl... | CAS号100-73-2 2-甲酰基-3,4-二氢吡喃 | CAS号106-69-4 1,2,6-己三醇 | CAS号25524-95-2 (Z)-6-(戊-2-烯-1-... | CAS号81683-96-7 6-(hydroxymethy... | CAS号4781-76-4 3,4-二氢吡喃甲胺

3,4-二氢-2H-吡喃-2-甲醛置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,以65%的收率获得2-羟甲基-3,4-二氢吡喃
参考文献:迈向 Chromene 大麻素库:固体支持物的组合方法
标题:迈向 Chromene 大麻素库:固体支持物的组合方法
摘要:提出了一种针对经典大麻素的新型固相合成方法.从固定化的水杨醛开始,通过包括裂解在内的四个原子经济步骤获得所需的 Thc 类似三环.所用反应的试剂(多米诺 Oxa-Michael-Aldol,Wittig 和 Diels-Alder)可以很容易地改变,为组合方法提供了基础.总产率为 20-60%.
Doi:10.1055/s-0030-1259300

专利信息

专利号:US-5545568-A
优先权日:1992-09-14
标题:Solid phase and combinatorial synthesis of compounds on a solid support
发明人：ELLMAN JONATHAN A
权利人:UNIV CALIFORNIA
摘要:Methods, compositions, and devices for synthesizing combinatorial libraries of various useful compounds, such as benzodiazepines, prostaglandins, β-turn mimetics and glycerol-derived drugs is described. In order to expediently synthesize such combinatorial libraries of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. This disclosure thus also describes an important extension of solid phase synthesis methods to nonpolymeric organic compounds.

专利号:US-6723798-B1
优先权日:2000-08-28
标 题:Resins having vinyl ether linker for the solid phase organic synthesis
发明人：YOO SUNGEUN; GONG YOUNGDAE; SEO JINSOO
权利人:KOREAN RES INST OF CHEMICAL TE
摘要:The present invention relates to a resin having a vinyl ether linker and more particularly, to a resin having a vinyl ether linker expressed by formula (I), useful for the synthesis of compounds having hetero atoms such as alcohol, thiol, imidazole, triazole and tetrazole by employing combinatorial chemical synthesis on solid supports.

专利号:WO-2024261319-A1
优先权日:2023-06-23
标题 :Methods of chemical synthesis of peptides
发明人：AL MUSAIMI OTHMAN; WILLIAMS DARYL ROBERT
权利人:IMPERIAL COLLEGE INNOVATIONS LTD
摘要:The present invention relates to methods for the synthesis of peptides and related compounds supported on a solid polymeric resin. The inventive method provides synthetic schemes that permit the coupling of two or more peptide fragments attached to the same polymeric support, in a fashion that allows access to previously unobtainable structures, and provides a more convenient and higher-yielding approach to known peptides, including those of commercial significance.

专利号:US-2024018099-A1
优先权日:2020-11-19
标题 :Synthesis of prostate specific membrane antigen (psma) ligands
发明人：ANDREAE FRITZ
权利人:NOVARTIS AG
摘要:The present disclosure relates to the synthesis of prostate specific membrane antigen (PSMA) ligands that are useful in the treatment of diseases like cancer. In particular, the disclosure relates to a method for synthesizing PSMA ligands having a glutamate-urea-lysine (GUL) moiety and a chelating agent that can comprise a radiometal.

专利号:US-2017320908-A1
优先权日:2014-11-19
标题 :Solid phase synthesis of cyclic amino acid molecules
发明人：HICKEY JENNIFER L; MANCUSO JOHN; MARSAULT ERIC; ROUGHTON ANDREW L; TREDER ADAM P; TREMBLEY MARIE-CLAUDE J; YUDIN ANDREI K; ZARETSKY SERGE
权利人:ENCYCLE THERAPEUTICS; GOVERNING COUNCIL OF THE UNIV OF TORONTO; UNIV SHERBROOKE
摘要:The present invention relates to cyclic amino acid molecules and methods of preparing the same, and in particular the macrocyclization of amino acids or linear peptides bound to a solid support.

专利号:US-12006541-B2
优先权日:2021-05-07
标题:Methods and apparatuses for generating peptides by synthesizing a portion of a design space to identify peptides having non-canonical amino acids
发明人：LEE FRANCIS; STECKBECK JONATHAN D; HOLSTE HANNES
权利人:PEPTILOGICS INC C; PEPTILOGICS INC
摘要:In one aspect, a computer-implemented automated flow synthesis platform configured to use an artificial intelligence (AI) engine is disclosed and includes a reaction chamber configured to synthesize a sequence, detectors configured to monitor the synthesis of the sequence in the reaction chamber, wherein the synthesis uses an automated flow process, and a computing device communicatively coupled to the detectors. The computing device receives measurements from the one or more detectors, wherein the measurements comprise a spectral profile at each coupling of each amino acid in the sequence, trains, using training data comprising the measurements, machine learning models to determine a synthesizing recipe that enables the sequence to be synthesized, wherein the synthesizing recipe comprises parameters used during the automated flow process to synthesize the sequence, and controls, using the synthesizing recipe, the synthesis of the sequence in the reaction chamber.