CAS: 55-55-0; 4-(Methylamino)Phenol Hemisulfate

上下游产品

acetic acid-(4-benzylidenamino-phenyl ester) dimethyl sulfate p-aminophenol hydr°Chloride 4-[(7-chloro-quinolin-4-yl)-methyl-amino]-phenol N-methyl-anilide)6-nitro-benzo[1,3]dioxole-5-carboxylic acid-(4-hydroxy-N-methyl-anilide) N-methyl-anilino)-ethanol2-(4-hydroxy-N-methyl-anilino)-ethanol N-methyl-(4-acetamido)phenol

4-氨基苯酚盐酸盐,硫酸二甲酯 反应生成 4-甲氨基苯酚硫酸盐
参考文献:Nag,Ahindra; Sarkar,Samir K.; Palit,Sunanda K.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1989,Vol. 28,# 1-11,P. 64
标题:Nag,Ahindra; Sarkar,Samir K.; Palit,Sunanda K.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1989,Vol. 28,# 1-11,P. 64

专利信息

专利号:US-6451543-B1
优先权日:1998-08-31
标题:Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
发明人：KOCHENDOERFER GERD G; HUNTER CHRISTIE L; KENT STEPHEN B H; BOTTI PAOLO
权利人:GRYPHON SCIENCES
摘要:The present invention relates to methods and compositions for lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides that are incorporated in a lipid matrix. The invention is exemplified in production of a prefolded membrane polypeptide embedded within a lipid matrix via stepwise chemoselective chemical ligation of unprotected peptide segments, where at least one peptide segment is embedded in a lipid matrix. Any chemoselective reaction chemistry amenable for ligation of unprotected peptide segments can be employed. Suitable lipid matrices include liposomes, micelles, cell membrane patches and optically isotropic cubic lipidic phase matrices. Prefolded synthetic and semi-synthetic membrane polypeptides synthesized according to the methods and compositions of the invention also permit site-specific incorporation of one or more detectable moieties, such as a chromophore, which can be conveniently introduced during synthesis. The methods and compositions of the invention have multiple uses. For example, they can be used to assay ligand binding to membrane polypeptides and domains comprising a receptor, and thus are extremely useful for structure/function studies, drug screening/selection/design, and diagnostics and the like, including high-throughput applications. The methods and compositions of the invention are particularly suited for FRET analyses of previously inaccessible membrane polypeptides.

专利号:WO-2024263718-A1
优先权日:2023-06-23
标 题:Synthesis of (-)-trans-δ9-tetrahydrocannabivarin and analogs thereof
发明人：ROGGEN MARKUS; SAMMIS GLENN M; ROBERTS MATTHEW
权利人:NALU BIO INC
摘要:A method is provided for the synthesis of (-)-trans-Δ9-tetrahydrocannabivarin (Δ9-THCV) and analogs thereof starting from a resorcinol reactant, such as divarinol, and a p-menthadienol reactant and proceeding through Δ8-THCV as intermediate. The initial step of the reaction between the resorcinol reactant and the p-menthadienol reactant is carried out in a solvent at elevated temperature in the presence of a Brønsted acid to form the Δ8 isomer. The Δ8 double bond is halogenated and the halogenated intermediate thus formed treated with a strong base to effect dehydrohalogenation and provide the desired product, Δ9-THCV, in high yield, with minimal or no remaining Δ8-THCV.

专利号:WO-2012088402-A1
优先权日:2010-12-22
标题 :Synthesis of conolidine and discovery of a potent non-opioid analgesic for pain
发明人：BOHN LAURA M; MICALIZIO GLENN C
权利人:SCRIPPS RESEARCH INST; BOHN LAURA M; MICALIZIO GLENN C
摘要:The first de novo synthetic pathway to the exceptionally rare C5-nor stemmadenine natural product, conolidine, and the first asymmetric synthesis of any member of this natural product class arc described. C5-nor stemmadenine compositions are also described. These compounds, for example,(+/- )-,(+)- and (-)-conolidine are potent and efficacious non-opioid analgesics in tonic and persistent pain.

专利号:US-2013143251-A1
优先权日:2010-06-01
标题:Expeditious synthesis of ubiquitinated peptide conjugates
发明人：BRIK ASHRAF; KUMAR AJISH; ERLICH LESLIE; SPASSER LIAT
权利人:BRIK ASHRAF; KUMAR AJISH; ERLICH LESLIE; SPASSER LIAT; UNIV BEN GURION
摘要:The present invention discloses a process for preparing ubiquinated peptide conjugates comprising a ubiquitin peptide residue UR attached at its C-terminus to a substrate peptide via a native isopeptide bond, this process comprising combining Native Chemical Ligation (NCL) and solid phase peptide synthesis (SPPS). Further are disclosed ubiquinated peptide conjugates containing a native isopeptide bond, as well as various uses thereof.

专利号:US-12006540-B2
优先权日:2015-09-28
标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
发明人：JU JINGYUE; LI XIAOXU; CHEN XIN; LI ZENGMIN; KUMAR SHIV; SHI SHUNDI; GUO CHENG; REN JIANYI; HSIEH MIN-KANG; CHIEN MINCHEN; TAO CHUANJUAN; ERTURK ECE; KALACHIKOV SERGEY; RUSSO JAMES J
权利人:UNIV COLUMBIA
摘要:Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

专利号:US-6229055-B1
优先权日:1996-04-12
标题 :Synthesis of fluorinated xanthene derivatives
发明人：KLAUBERT DIETER H; GEE KYLE R
权利人:MOLECULAR PROBES INC
摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.