CAS: 56119-28-9; (4Ar,6S,7R,8R,8As)-6-(Ethylthio)-2-Phenylhexahydropyrano[3,2-D][1,3]Dioxine-7,8-Diol

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97232-16-1 1208999-29-4 56119-30-3

上下游产品

benzaldehyde ethyl 1-thio-β-D-galactopyranoside benzaldehyde dimethyl acetal toluene-4-sulfonic acidS-ethyl-6-O-(phenylmethyl)-1-thio-β-D-galactopyranoside Ethyl 3-O-benzoyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside (2R,3R,4R,5R,6R)-5-Benzyloxy-6-benzyloxymethyl-2-((2R,3R,4R,5S,6S)-3,5-bis-benzyloxy-2-methoxy-6-methyl-tetrahydro-pyran-4-yloxy)-tetrahydro-pyran-3,4-diol Acetic acid (2R,3R,4S,5S,6R)-4-acetoxy-6-benzyloxymethyl-2-((2R,3R,4R,5S,6S)-3,5-bis-benzyloxy-2-methoxy-6-methyl-tetrahydro-pyran-4-yloxy)-5-hydroxy-tetrahydro-pyran-3-yl ester

苯甲醛,1-硫代-β-D-乙基半乳糖苷置于ytterbium(Iii) Triflate,原甲酸三甲酯体系中,用 Neat (No Solvent) 作为反应溶剂,化学反应 2.0H,以89%的收率获得产物乙基 4,6-O-亚苄基硫代-Beta-D-半乳糖苷
参考文献:碳水化合物缩醛功能化的三种无溶剂催化方法及其对一锅反应生成正交保护的构建基块的适用性
标题:碳水化合物缩醛功能化的三种无溶剂催化方法及其对一锅反应生成正交保护的构建基块的适用性
摘要:开发了三种替代方案,以在弱酸性,无溶剂的条件下选择性地将缩醛基团安装在碳水化合物和多元醇上.一种方案是基于在室温下的二醇/醛缩合,其中乙酰解过程用于活化羰基组分.第二种方法是基于在高温下原酸酯介导的羰基组分的活化.第三方案相反是要求一种转缩醛化机制.这些方法的结合使得可以在非常简单的实验条件下,在空气中短时间内访问各种缩醛保护的构建基块.
DOI:10.1002/adsc.201500745

专利信息

专利号:US-6723843-B2
优先权日:1996-08-26
标题:Oligosaccharide synthesis
发明人：TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
权利人:ALCHEMIA PTY LTD
摘要:The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-glycoside type to a polymer support. The invention provides reagents, reagent kits and methods for solid-phase oligosaccharide synthesis.